Pakozdy A, Halasz P, Klang A
University Clinic for Small Animals, Clinical Department for Companion Animals and Horses, University of Veterinary Medicine, Vienna, Austria.
J Vet Intern Med. 2014 Mar-Apr;28(2):255-63. doi: 10.1111/jvim.12297. Epub 2014 Jan 17.
The veterinary literature on epilepsy in cats is less extensive than that for dogs. The present review summarizes the most important human definitions related to epilepsy and discusses the difficulties in applying them in daily veterinary practice. Epileptic seizures can have a wide range of clinical signs and are not necessarily typical in all cases. Whether a seizure event is epileptic can only be suspected based on clinical, laboratory, and neuroimaging findings as electroencephalography diagnostic techniques have not yet been developed to a sufficiently accurate level in veterinary medicine. In addition, the present review aims to describe other diagnoses and nonepileptic conditions that might be mistaken for epileptic seizures. Seizures associated with hippocampal lesions are described and discussed extensively, as they seem to be a special entity only recognized in the past few years. Furthermore, we focus on clinical work-up and on treatment that can be recommended based on the literature and summarize the limited data available relating to the outcome. Critical commentary is provided as most studies are based on very weak evidence.
关于猫癫痫的兽医文献不如关于狗的广泛。本综述总结了与癫痫相关的最重要的人类定义,并讨论了在日常兽医实践中应用这些定义的困难。癫痫发作可能有广泛的临床症状,并非在所有情况下都具有典型性。由于兽医医学中的脑电图诊断技术尚未发展到足够准确的水平,只能根据临床、实验室和神经影像学检查结果怀疑某一发作事件是否为癫痫发作。此外,本综述旨在描述可能被误诊为癫痫发作的其他诊断和非癫痫性疾病。与海马病变相关的发作将被广泛描述和讨论,因为它们似乎是仅在过去几年才被认识到的一种特殊情况。此外,我们将重点关注临床检查和基于文献可推荐的治疗方法,并总结与预后相关的有限数据。由于大多数研究基于非常薄弱的证据,因此提供了批判性评论。