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辅助性 T 细胞 17 在自身免疫、炎症和动脉粥样硬化中的作用。

Th17 cells at the crossroads of autoimmunity, inflammation, and atherosclerosis.

机构信息

Department of Biomedical Imaging, Genentech Inc., South San Francisco, CA 94080, USA.

Department of Immunology, Genentech Inc., South San Francisco, CA 94080, USA.

出版信息

Immunity. 2014 Jan 16;40(1):10-2. doi: 10.1016/j.immuni.2013.12.006.

DOI:10.1016/j.immuni.2013.12.006
PMID:24439264
Abstract

The connection between inflammation, autoimmunity, and atherosclerosis is long established. In this issue of Immunity, Lim et al. (2014) demonstrate that oxidized low-density lipoprotein is one of the key environmental factors driving the development of inflammatory T helper 17 cells in atherosclerosis.

摘要

炎症、自身免疫和动脉粥样硬化之间的联系由来已久。在本期《免疫》杂志中,Lim 等人(2014)证明氧化型低密度脂蛋白是驱动动脉粥样硬化中炎症性辅助性 T 细胞 17 发展的关键环境因素之一。

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