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用于重度气管软化症的主动脉固定术的手术入路。

Surgical approaches to aortopexy for severe tracheomalacia.

机构信息

Department of General Surgery and Esophageal Atresia Treatment Program, Boston Children's Hospital/Harvard Medical School, Boston, MA, USA.

Department of General Surgery and Esophageal Atresia Treatment Program, Boston Children's Hospital/Harvard Medical School, Boston, MA, USA.

出版信息

J Pediatr Surg. 2014 Jan;49(1):66-70; discussion 70-1. doi: 10.1016/j.jpedsurg.2013.09.036. Epub 2013 Oct 16.

Abstract

PURPOSE

The purpose of this study was to determine the outcomes among three different surgical approaches for performing an aortopexy to treat severe tracheomalacia (STM).

METHODS

A retrospective review was performed for all patients who underwent an aortopexy by pediatric surgeons at a single institution during 1997-2012. Data collected included details of the operative approaches and clinical results. The data were analyzed using Chi-square and Fisher exact test.

RESULTS

Forty-one patients underwent an aortopexy. The operation was chosen by the surgeon and not randomized. Exposure was by partial sternotomy (PS) (20), open thoracotomy (12), or thoracoscopic approach (7). Only the PS approach was done by a single team. All groups showed improvement in work of breathing, prevention of severe respiratory distress, and acute life threatening events. These effects were more dramatic for the PS group, especially regarding oxygen and/or ventilator dependence and the ability to undergo tracheostomy decannulation. Among the sixteen patients with failure-to-thrive before successful aortopexy by any technique, ten demonstrated significant improvement in their growth (p=0.025). The recurrence rate for the thoracoscopic approach was 38%, and there were no recurrences in the partial sternotomy and the thoracotomy groups, 38% vs 0% vs 0%, p=0.005. Simultaneous bronchoscopy was utilized more commonly in the PS group compared to the thoracotomy and thoracoscopic group, 95% vs 62% vs 38%.

CONCLUSIONS

In this series, the partial sternotomy technique had the most reliable resolution of symptoms and no recurrence requiring reoperation. The PS approach to STM has the technical advantages of an improved exposure with equal access to the vessels over the right and left mainstem bronchi, as well as the trachea and a more specific elevation of the arteries, including suspension of the pulmonary arteries and trachea itself when desirable. Simultaneous bronchoscopy during aortopexy and an experienced team also likely contribute to improved outcomes. The variations in populations, follow-up, and use of continuous intraoperative bronchoscopy, however, make firm conclusions difficult.

摘要

目的

本研究旨在确定三种不同手术入路行主动脉固定术治疗严重气管软化(TM)的治疗结果。

方法

对 1997 年至 2012 年间在一家机构接受小儿外科医生主动脉固定术的所有患者进行回顾性分析。收集的数据包括手术入路和临床结果的详细信息。数据分析采用卡方检验和 Fisher 确切概率检验。

结果

41 例患者接受了主动脉固定术。手术方式由外科医生选择,而非随机。手术入路包括胸骨部分劈开(PS)(20 例)、开胸(12 例)和胸腔镜(7 例)。仅 PS 入路由单一团队完成。所有组均显示呼吸做功改善、预防严重呼吸窘迫和急性危及生命事件。PS 组的效果更为显著,尤其是在氧合和/或呼吸机依赖以及行气管造口拔管的能力方面。在所有成功接受主动脉固定术的患者中,有 16 例在接受手术前存在生长不良,其中 10 例生长显著改善(p=0.025)。胸腔镜组的复发率为 38%,PS 组和开胸组无复发,分别为 38%、0%和 0%,p=0.005。PS 组较开胸组和胸腔镜组更常同时行支气管镜检查,分别为 95%、62%和 38%。

结论

在本系列中,PS 技术治疗严重气管软化的症状缓解最可靠,且无再次手术的复发。PS 入路治疗 TM 的技术优势为血管暴露更好,右侧和左侧主支气管、气管以及更具体的动脉抬高(包括肺动脉和气管本身)均具有同等的操作通道。在主动脉固定术中同时行支气管镜检查和经验丰富的团队也可能有助于改善结果。然而,由于人群、随访和连续术中支气管镜检查的使用存在差异,难以得出明确的结论。

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