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腹腔镜幽门肌切开术后肠内营养与随意喂养的比较:一项前瞻性随机试验。

Protocol versus ad libitum feeds after laparoscopic pyloromyotomy: a prospective randomized trial.

机构信息

The Center for Prospective Clinical Trials The Children's Mercy Hospital Kansas City, MO.

The Center for Prospective Clinical Trials The Children's Mercy Hospital Kansas City, MO.

出版信息

J Pediatr Surg. 2014 Jan;49(1):129-32; discussion 132. doi: 10.1016/j.jpedsurg.2013.09.044. Epub 2013 Oct 8.

Abstract

BACKGROUND

We conducted a prospective, randomized trial comparing protocol to ad libitum (ad lib) feeding after laparoscopic pyloromyotomy.

METHODS

Infants undergoing laparoscopic pyloromyotomy were randomized to protocol versus ad lib feeding strategies. The protocol started with Pedialyte® two hours post-operative. This was repeated by another round of Pedialyte®, then two rounds of half-strength formula or breast milk, followed by two rounds of full strength formula or breast milk, followed by the home feeding regimen, at which time the patient was discharged if feeding well. The ad lib group was allowed formula or breast milk two hours after the operation and considered for discharge after tolerating three consecutive feeds. The primary outcome variable was the length of postoperative hospitalization.

RESULTS

One hundred fifty infants were enrolled between January 2010 and December 2011. There were no differences in patient characteristics at presentation. While the ad lib group reached goal feeds sooner than the protocol group, this did not translate into a difference in duration of postoperative hospitalization. There were more patients with emesis in the ad lib group after goal feeding was reached, but no difference in readmissions.

CONCLUSION

Ad lib feeding allows patients to reach goal feeds more rapidly than protocol feeding following laparoscopic pyloromyotomy. However, this goal is usually reached beyond discharge hours, resulting in a similar duration of hospitalization.

摘要

背景

我们进行了一项前瞻性、随机试验,比较了腹腔镜幽门肌切开术后的协议喂养与随意喂养。

方法

接受腹腔镜幽门肌切开术的婴儿被随机分为协议喂养组和随意喂养组。方案组在术后两小时开始使用Pedialyte®。这被另一轮Pedialyte®重复,然后是两轮半强度配方或母乳,接着是两轮全强度配方或母乳,然后是家庭喂养方案,此时如果喂养良好,患者就可以出院。随意喂养组在手术后两小时内可使用配方奶或母乳,并在耐受连续三次喂养后考虑出院。主要观察变量是术后住院时间。

结果

2010 年 1 月至 2011 年 12 月期间共纳入 150 名婴儿。入院时患者特征无差异。虽然随意喂养组比方案喂养组更快地达到目标喂养量,但这并没有转化为术后住院时间的差异。在达到目标喂养量后,随意喂养组中有更多的患者出现呕吐,但再入院率没有差异。

结论

与腹腔镜幽门肌切开术后的协议喂养相比,随意喂养可使患者更快地达到目标喂养量。然而,这一目标通常在出院时间之后达到,导致住院时间相似。

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