Karki S, Joshi K S, Regmi S, Gurung R B, Malla B
Department of Radiodiagnosis and Imaging,Dhulikhel Hospital- Kathmandu University Hospital Kathmandu University School of medical Science, Dhulikhel Hospital, Kavre, Nepal.
Department of Internal medicine,Dhulikhel Hospital- Kathmandu University Hospital Kathmandu University School of medical Science, Dhulikhel Hospital, Kavre, Nepal.
Kathmandu Univ Med J (KUMJ). 2013 Jul-Sep;11(43):237-40. doi: 10.3126/kumj.v11i3.12512.
The diagnosis of obstructive jaundice relies on proper history taking, clinical examination, laboratory investigations and different non invasive imaging modalities like Ultrasonography (USG), Cholangio Computed Tomography (CCT), Magnetic resonance Imaging (MRI) with Magnetic Resonance Cholangio Pancreatography (MRCP) and invasive modalities like endoscopic retrograde cholangiography (ERCP) and percutaneous trans hepatic cholangiography (PTC).
To compare the role of ultrasound with endoscopic retrograde cholangiography and to determine the major causes of obstructive jaundice in our prospect.
This was a prospective, analytical study conducted on 88 patients presenting to Department of Radiodiagnosis and Imaging at Dhulikhel Hospital-Kathmandu University hospital from March 2011 to August 2012 with clinical diagnosis of obstructive jaundice. Sonographic evaluation was performed in Siemens acusion x-150 and x-300. The final diagnosis was made by endoscopic retrograde cholangiography and /or surgery and confirmed histopathologically.
The most common benign causes of obstructive jaundice were choledocholithiasis (63%), CBD stricture (12.3%), cholangitis (8%) and pancreatitis (6.85%) whereas cholangio carcinoma (6.85%) and carcinoma head of pancreas (4%) comprised of the malignant causes . Ultrasonography had sensitivity of 100% and specificity of 89% in detecting choledocholithiasis. It was found to be 98.78% sensitive and 83.33% specific in cholangiocarcinoma. Similarly in pancreatitis, the sensitivity of ultrasonography was 97.59% and sensitivity was 66.67%.
Ultrasonography acts as a valuable diagnostic imaging modality in detecting the causes of obstructive jaundice. Due to its easy availability, non invasive nature and cost effectiveness, it can be considered as the first line imaging technique/ tool. ERCP is the invasive imaging tool and can be used for both diagnostic and therapeutic purpose.
梗阻性黄疸的诊断依赖于详细的病史采集、临床检查、实验室检查以及不同的非侵入性成像方式,如超声检查(USG)、胆管计算机断层扫描(CCT)、磁共振成像(MRI)及磁共振胰胆管造影(MRCP),还有侵入性检查方式,如内镜逆行胰胆管造影(ERCP)和经皮肝穿刺胆管造影(PTC)。
比较超声与内镜逆行胰胆管造影的作用,并确定我们研究中梗阻性黄疸的主要病因。
这是一项前瞻性分析研究,对2011年3月至2012年8月在加德满都大学杜利凯尔医院放射诊断与影像科就诊且临床诊断为梗阻性黄疸的88例患者进行研究。使用西门子acusion x - 150和x - 300进行超声评估。最终诊断通过内镜逆行胰胆管造影和/或手术做出,并经组织病理学证实。
梗阻性黄疸最常见的良性病因是胆总管结石(63%)、胆总管狭窄(12.3%)、胆管炎(8%)和胰腺炎(6.85%),而恶性病因包括胆管癌(6.85%)和胰头癌(4%)。超声检查在检测胆总管结石方面的敏感性为100%,特异性为89%。在胆管癌中,其敏感性为98.78%,特异性为83.33%。同样,在胰腺炎中,超声检查的敏感性为97.59%,特异性为66.67%。
超声检查是检测梗阻性黄疸病因的一种有价值的诊断成像方式。由于其易于获得、非侵入性和成本效益,可被视为一线成像技术/工具。ERCP是一种侵入性成像工具,可用于诊断和治疗目的。