Farrukh Syed Zea-Ul-Islam, Siddiqui Arif Rasheed, Haqqi Syed Afzal, Muhammad Asif Jan, Dheddi Abdul Samad, Khalid Saad Khalid
Department of Gastroenterology and Hepatology Patel Hospital Karachi, Pakistan.
J Ayub Med Coll Abbottabad. 2016 Oct-Dec;28(4):650-652.
Ultrasonography has proven to be quite effective in differentiating hepatocellular from obstructive cause of jaundice in various studies. This study was conducted with the aim to determine the efficacy of ultrasonography and Endoscopic Retrograde Cholangio-Pancreatography (ERCP) in the diagnosis of obstructive reason of jaundice.
In this descriptive case series, 200 patients with >15 years age of either gender with cholestatic liver enzymes were included, i.e., those patients who had an ultrasound prior to ERCP at the department of gastroenterology of Patel Hospital, Karachi. Patients known to have liver disease with cholestatic jaundice had imaging other than ultrasound were excluded. The results of ultrasonography and ERCPs were compared in particularly looking for the cause of obstruction.
Out of total 200 patients, mean age was 41.22±12.46 years with 107 (53.5%) females. Ability of ultrasound in correctly diagnosing obstructive reason for stone CBD was found to be 72.5%, dilated CBD without reason 41.7%, proximal obstruction, 63.15%, distal CBD obstruction 60%, and sludge 66.7%. Overall ability of ultrasound in correctly diagnosing the cause of obstruction was 64.17%.
Ultrasound is recommended as the initial examination, which provides a guide to choose patients for either a more advanced noninvasive imaging like MRCP or to an invasive procedure like ERCP.
在各项研究中,超声检查已被证明在区分肝细胞性黄疸和梗阻性黄疸病因方面相当有效。本研究旨在确定超声检查和内镜逆行胰胆管造影(ERCP)在诊断黄疸梗阻原因方面的有效性。
在这个描述性病例系列中,纳入了200例年龄大于15岁、患有胆汁淤积性肝酶异常的患者,即那些在卡拉奇帕特尔医院胃肠病科接受ERCP检查前进行过超声检查的患者。已知患有胆汁淤积性黄疸且有肝脏疾病且进行过超声以外影像学检查的患者被排除。特别对比了超声检查和ERCP检查结果以寻找梗阻原因。
在总共200例患者中,平均年龄为41.22±12.46岁,女性107例(53.5%)。超声正确诊断胆总管结石梗阻原因的能力为72.5%,无原因胆总管扩张为41.7%,近端梗阻为63.15%,胆总管远端梗阻为60%,胆泥为66.7%。超声正确诊断梗阻原因的总体能力为64.17%。
建议将超声作为初始检查,它可为选择患者进行更先进的无创成像如磁共振胰胆管造影(MRCP)或侵入性检查如ERCP提供指导。