对致突变性硝基芳烃高度敏感的鼠伤寒沙门氏菌新测试菌株。
New tester strains of Salmonella typhimurium highly sensitive to mutagenic nitroarenes.
作者信息
Watanabe M, Nohmi T, Ishidate M
机构信息
Division of Mutagenesis, National Institute of Hygienic Sciences, Tokyo, Japan.
出版信息
Biochem Biophys Res Commun. 1987 Sep 30;147(3):974-9. doi: 10.1016/s0006-291x(87)80165-1.
PMID:2444227
Abstract
The nitroreductase and acetyltransferase genes of Salmonella typhimurium TA1538 have been cloned into pBR322. When transformed into TA1538 derivatives, these plasmids provided the basis for an extremely sensitive assay for the detection of mutagenic nitroarenes.
摘要
鼠伤寒沙门氏菌TA1538的硝基还原酶基因和乙酰转移酶基因已被克隆到pBR322中。当将这些质粒转化到TA1538衍生物中时，它们为检测致突变性硝基芳烃提供了一种极其灵敏的检测方法的基础。
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