Department of Neurology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55901, USA.
Transl Neurodegener. 2014 Jan 21;3(1):2. doi: 10.1186/2047-9158-3-2.
Deep brain stimulation (DBS) is an effective surgical treatment for medication-refractory movement disorders, and has been approved by the United States Food and Drug Administration for treatment of dystonia. The success of DBS in the treatment of dystonia depends on our understanding of the anatomy and physiology of this disorder and close collaboration between neurosurgeons, neurologists, clinical neurophysiologists, neuroradiologists and neuropsychologists. Currently, pallidal DBS is an established treatment option for medically refractive dystonia. This review is intended to provide a comprehensive review of the use of DBS for dystonia, focusing mainly on the surgical aspects, clinical outcome, MRI findings and side effects of DBS.
脑深部电刺激(DBS)是一种有效的手术治疗方法,用于治疗药物难治性运动障碍,已被美国食品和药物管理局批准用于治疗肌张力障碍。DBS 治疗肌张力障碍的成功取决于我们对这种疾病的解剖学和生理学的理解,以及神经外科医生、神经科医生、临床神经生理学家、神经放射学家和神经心理学家之间的密切合作。目前,苍白球 DBS 是治疗药物难治性肌张力障碍的一种既定治疗选择。本综述旨在全面回顾 DBS 治疗肌张力障碍的应用,主要关注手术方面、临床结果、MRI 发现和 DBS 的副作用。