[鼻咽腺样囊性癌的影像学及临床特征]

[Imaging and clinical features of nasopharyngeal adenoid cystic carcinoma].

作者信息

Yin Jie, Liu Li-zhi, Gu Mo-fa

机构信息

Department of Radiology of Chongqing Traditonal Chinese Medicine Hospital, Chongqing 400021, China.

Center for Medical Imaging and Interventional Radiology, SUN Yat-sen University Cancer Center, Guangzhou 510060, China. Email:

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2013 Nov;48(11):930-3.

PMID:24444639

Abstract

OBJECTIVE

To analyze the spreading patterns nasopharyngeal carcinoma and nasopharyngeal adenoid cystic carcinoma.

METHODS

Eighteen pathologically confirmed consecutive cases of adenoid cystic carcinomas (ACC) and 182 cases of untreated nasopharyngeal carcinomas (NPC) were reviewed.

RESULTS

Compared with NPC, ACC had higher rates of T4 disease (14.3% vs 38.9%,χ(2) = 7.197, P = 0.007) and paralyzed cranial nerve (6.0% vs 38.9%,χ(2) = 37.936, P < 0.001) . There was no significant difference in skull base invasion rates between 2 groups (53.3% vs 66.7%,χ(2) = 1.181, P = 0.277) . ACC had higher rates of MRI-detected cranial nerve canal invasion (32.4% vs 55.6%,χ(2) = 3.881, P = 0.049) and cavernous sinus invasion (13.7% vs 33.3%,χ(2) = 7.710, P = 0.028) than NPC. Lymph node metastasis occurred in 64.8% of ACC, and 11.1% of NPC (χ(2) = 19.699, P < 0.001) .

CONCLUSION

ACC has a higher rate of cranial nerve invasion and NPC has a higher rate of lymphatic metastasis.

摘要

目的

分析鼻咽癌和鼻咽腺样囊性癌的扩散模式。

方法

回顾性分析18例经病理确诊的腺样囊性癌（ACC）连续病例和182例未经治疗的鼻咽癌（NPC）病例。

结果

与鼻咽癌相比，腺样囊性癌T4期疾病发生率更高（14.3%对38.9%，χ(2)=7.197，P=0.007），颅神经麻痹发生率更高（6.0%对38.9%，χ(2)=37.936，P<0.001）。两组颅底侵犯率无显著差异（53.3%对66.7%，χ(2)=1.181，P=0.277）。腺样囊性癌MRI检测到的颅神经管侵犯率（32.4%对55.6%，χ(2)=3.881，P=0.049）和海绵窦侵犯率（13.7%对33.3%，χ(2)=7.710，P=0.028）高于鼻咽癌。腺样囊性癌淋巴结转移发生率为64.8%，鼻咽癌为11.1%（χ(2)=19.699，P<0.001）。