鼻咽癌与鼻咽部腺样囊性癌在MRI上的扩展模式差异。

Differences in extension patterns between adenoid cystic carcinoma of the nasopharynx and nasopharyngeal carcinoma on MRI.

作者信息

Dong Jun, Tian Li, Li Sheng, Mo Yunxian, Liu Lizhi, Zhong Rui

机构信息

Department of VIP Patients, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine East Dong Feng Road 651, Guangzhou 510060, Guangdong, P. R. China.

Department of Medical Imaging and Interventional Radiology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine East Dong Feng Road 651, Guangzhou 510060, Guangdong, P. R. China.

出版信息

Int J Clin Exp Pathol. 2015 Dec 1;8(12):15960-8. eCollection 2015.

PMID:26884870

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4730083/

Abstract

OBJECTIVE

This study aimed to map differences in extension patterns between adenoid cystic carcinoma (ACC) of the nasopharynxandnasopharyngeal carcinomaon magnetic resonance imaging (MRI) and provide more information for treatments.

METHODS

MRI examinations and clinical records were reviewed in 18 patients with ACC of the nasopharynx and 182 patients with nasopharyngeal carcinoma (NPC). All patients had biopsy to confirm diagnosis. Differences between NPC and ACC in terms of extension patterns were identified by the retrospective analysis of images from patients undergoing MRI.

RESULTS

Patients with ACC of the nasopharynx obtained a higher rate of staging T4 (14.3% vs. 38.9%, P = 0.007) and paralyzed cranial nerves (6.0% vs. 38.9%, P < 0.001). Epstein-Barr (EB) virus infection was not correlated with ACC incidence. No significant difference was observed in invasion to skull base between ACC of the nasopharynx and NPC (53.3% vs. 66.7%, P = 0.277). Involvement of cranial nerve canal (32.4% vs. 55.6%, P = 0.049) and cavernous sinus (13.7% vs. 33.3%, P = 0.028) was more frequently detected by MRI on patients with ACC of the nasopharynx. Lymph node metastasis was infrequently diagnosed in patients with ACC of the nasopharynx.

CONCLUSION

As seen on MRI images, ACC of the nasopharynx is characterized by a high incidence of perineural invasion, frequent and aggressive local infiltration, and infrequently, lymph node metastasis.

摘要

目的

本研究旨在通过磁共振成像（MRI）描绘鼻咽腺样囊性癌（ACC）与鼻咽癌在扩展模式上的差异，为治疗提供更多信息。

方法

回顾性分析18例鼻咽ACC患者和182例鼻咽癌（NPC）患者的MRI检查及临床记录。所有患者均经活检确诊。通过对接受MRI检查患者的图像进行回顾性分析，确定NPC和ACC在扩展模式方面的差异。

结果

鼻咽ACC患者的T4期发生率较高（14.3%对38.9%，P = 0.007），颅神经麻痹发生率也较高（6.0%对38.9%，P < 0.001）。爱泼斯坦-巴尔（EB）病毒感染与ACC发病率无关。鼻咽ACC与NPC在侵犯颅底方面无显著差异（53.3%对66.7%，P = 0.277）。MRI更常检测到鼻咽ACC患者累及颅神经管（32.4%对55.6%，P = 0.049）和海绵窦（13.7%对33.3%，P = 0.028）。鼻咽ACC患者很少诊断出淋巴结转移。