Krc I, Macák J, Krcová V, Zahálková J
Palacky University, Second and First Medical Clinic, Olomouc, CSSR.
Folia Haematol Int Mag Klin Morphol Blutforsch. 1987;114(3):367-75.
Richter's syndrome represents an acute transformation of chronic lymphocytic leukaemia or other type of low-grade malignant non-Hodgkin lymphoma to highly malignant anaplastic large-cell lymphoma. The prognosis of this complication is highly unfavourable. The authors report on eight cases of Richter's syndrome observed in a series of 198 patients with the clinical diagnosis of chronic lymphocytic leukaemia and evaluate some clinicopathological and immunological peculiarities of this disease.
里氏综合征表现为慢性淋巴细胞白血病或其他类型的低度恶性非霍奇金淋巴瘤急变为高度恶性的间变性大细胞淋巴瘤。这种并发症的预后非常不利。作者报告了在198例临床诊断为慢性淋巴细胞白血病的患者系列中观察到的8例里氏综合征病例，并评估了该疾病的一些临床病理和免疫学特点。
