van der Walt J D, Clear Hill B G, Temple L N
S Afr Med J. 1983 Sep 24;64(13):496-8.
A patient suffering from typical chronic lymphocytic leukaemia (CLL) developed a rapidly fatal high-grade lymphoma (Richter's syndrome). In cases of CLL Richter's syndrome must be distinguished from coexistent Hodgkin's disease and prolymphocytic transformation. The prognosis is dismal but not hopeless if the condition is treated early. Lymph node biopsy is essential for diagnosis and treatment.
一名患有典型慢性淋巴细胞白血病（CLL）的患者发展为快速致命的高级别淋巴瘤（里氏综合征）。在CLL病例中，里氏综合征必须与并存的霍奇金病和幼淋巴细胞转化相鉴别。如果早期治疗，预后虽差但并非毫无希望。淋巴结活检对诊断和治疗至关重要。
