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[各种血栓形成形式的解剖学和医学实验室对照]

[Anatomical and medical laboratory parallels of various forms of thrombus formation].

作者信息

Angelov A, Alachverdjan R P

机构信息

Medizinischen Akademie in Varna (Bulgarien), Lehrstuhl für Pathologische Anatomie.

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1987;114(3):414-22.

PMID:2444516
Abstract

77 patients who had suffered from various diseases and had died under clinical circumstances of thromboembolic complications were systematically examined in clinical and morphological respect. Depending on the pathological-anatomical character of thrombus formation determined they were classified into 4 groups: 1. Massive venous thromboses with embolus of the lung; 2. Disseminated intravasal coagulation; 3. Locally limited, mainly arterial thromboses or some microthromboses; 4. Without any thrombotic complications. A distinct dependence between the changes in the standard values of the coagulation status (fibrinogen, thrombocytes, prothrombin time, bleeding and coagulation time) and the character and extent of thrombotic processes could not be detected. It is solely the level of fibrin splitting products which, to a certain degree, reflects the extent and spread of thrombotic processes.

摘要

对77例患有各种疾病且在临床血栓栓塞并发症情况下死亡的患者进行了临床和形态学方面的系统检查。根据所确定的血栓形成的病理解剖特征,将他们分为4组:1. 伴有肺栓塞的大量静脉血栓形成;2. 弥散性血管内凝血;3. 局部局限性血栓形成,主要为动脉血栓或一些微血栓;4. 无任何血栓形成并发症。未发现凝血状态标准值(纤维蛋白原、血小板、凝血酶原时间、出血和凝血时间)的变化与血栓形成过程的特征和程度之间存在明显相关性。仅纤维蛋白降解产物的水平在一定程度上反映了血栓形成过程的程度和范围。

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