Angelov A, Zekov C
Z Erkr Atmungsorgane. 1984;162(3):256-61.
34 patients, died of chronic respiratory insufficiency, as a result of chronic obstructive pulmonary disease (COPD), are the subject of clinical-anatomical analysis. In 18 (53 +/- 17%) of them could be found thromboembolic complications more often developed as subacute or chronic intravascular coagulation, but evident changes could not be always met in the clotting system. The most characteristic feature is the raising of fibrin-degradation products and the reduction of antithrombin III. The necessity of dynamic trace of coagulation and haemorrheological data in patients with COPD in the stage of heavy chronic respiratory insufficiency is emphasized.
34例因慢性阻塞性肺疾病(COPD)死于慢性呼吸功能不全的患者成为临床解剖分析的对象。其中18例(53±17%)出现血栓栓塞并发症,多发展为亚急性或慢性血管内凝血,但凝血系统并非总能见到明显变化。最典型的特征是纤维蛋白降解产物升高和抗凝血酶III降低。强调了对处于重度慢性呼吸功能不全阶段的COPD患者凝血和血液流变学数据进行动态追踪的必要性。