Tainio H, Vaalasti A, Rechardt L
Institute of Biomedical Sciences, University of Tampere, Finland.
Histochem J. 1987 Jun-Jul;19(6-7):375-80. doi: 10.1007/BF01680455.
The distribution in immunoreactivities towards atrial natriuretic peptide, calcitonin gene-related peptide, galanin and substance P were demonstrated in human skin at the light and electron microscopic levels. Nerves immunoreactive to the first three of these peptides were found around eccrine sweat glands, whereas only a few positively-labelled nerve fibres could be seen around apocrine glands. At the ultrastructural level, immunoreactivity to the neuropeptides was localized in the large dense-cored vesicles of the nerve terminals. No immunoreactivity to substance P could be detected around sweat glands. In addition to these findings, the four types of immunoreactivity were seen in the thick preterminal nerve bundles.
在光镜和电镜水平上，对人皮肤中抗心钠素、降钙素基因相关肽、甘丙肽和P物质的免疫反应分布进行了研究。发现对上述前三种肽有免疫反应的神经位于外分泌汗腺周围，而在顶泌汗腺周围仅能看到少数阳性标记的神经纤维。在超微结构水平上，神经肽的免疫反应定位于神经末梢的大致密核心小泡中。在汗腺周围未检测到对P物质的免疫反应。除了这些发现外，在粗大的终末前神经束中也观察到了这四种免疫反应类型。
