Zoller Marc, Walther Stefan
Anasthesiol Intensivmed Notfallmed Schmerzther. 2014 Jan;49(1):8-11. doi: 10.1055/s-0033-1363907. Epub 2014 Jan 20.
Pseudocholinesterase or butyrylcholinesterase (BChE) inactivates the relaxant drugs mivacurium and suxamethonium. A deficiency in plasma activity of this enzyme may result in prolonged muscular paralysis and subsequently the need for an extended duration of mechanical ventilation. We report the case of a 65-year-old patient who was diagnosed with butyrylcholinesterase deficiency for the first time during elective surgery. Neuromuscular monitoring constitutes a central diagnostic asset in ensuring patient safety.
假性胆碱酯酶或丁酰胆碱酯酶（BChE）可使肌松药米库氯铵和琥珀胆碱失活。该酶血浆活性缺乏可能导致肌肉麻痹时间延长，进而需要延长机械通气时间。我们报告一例65岁患者，其在择期手术期间首次被诊断为丁酰胆碱酯酶缺乏。神经肌肉监测是确保患者安全的核心诊断手段。
