Fry Joanna K, Burney Derek, Hottinger Heidi, Fabiani Michelle, Feagin Clint
Gulf Coast Veterinary Specialists, Houston, TX.
J Am Anim Hosp Assoc. 2014 Mar-Apr;50(2):141-7. doi: 10.5326/JAAHA-MS-5984. Epub 2014 Jan 20.
An approximately 8 yr old castrated male Labrador retriever presented for evaluation of weight loss, stranguria, and pollakiuria. Lysis of the proximal one-third of the os penis was diagnosed on abdominal radiographs, and a positive contrast urethrography revealed a smoothly marginated filling defect along the dorsal aspect of the urethra at the level of the radiographically observed osteolysis. Regional ultrasound revealed an echogenic mass at the proximal aspect of the os penis with a severely irregular and discontinuous periosteal surface. A penile hemangiosarcoma (HSA) was confirmed on histopathologic evaluation after a penile amputation and scrotal urethrostomy were performed. Although HSA is a common malignant neoplasm in dogs, lysis of the os penis has not previously been documented. Adjunctive chemotherapy, although recommended, was declined, and the patient survived 236 days postoperatively. That survival time is considerably longer than the average survival time for patients with HSA, other than cutaneous forms of HSA. Although an uncommon presentation, HSA of the penis should be considered a differential diagnosis in older canines with signs of lower urinary tract disease, especially in breeds that have been documented to be predisposed to HSA.
一只约8岁的去势雄性拉布拉多猎犬因体重减轻、排尿困难和尿频前来评估。腹部X光片诊断为阴茎骨近端三分之一溶解,阳性造影尿道造影显示在X光片观察到的骨质溶解水平处,尿道背侧有边缘光滑的充盈缺损。局部超声显示阴茎骨近端有一个回声团块,骨膜表面严重不规则且不连续。在进行阴茎截肢和阴囊尿道造口术后,组织病理学评估确诊为阴茎血管肉瘤(HSA)。虽然HSA是犬类常见的恶性肿瘤,但阴茎骨溶解此前未见报道。尽管建议进行辅助化疗,但主人拒绝了,该患者术后存活了236天。该存活时间比HSA患者(非皮肤型HSA)的平均存活时间长得多。虽然表现不常见,但阴茎HSA应被视为老年犬下尿路疾病症状的鉴别诊断,尤其是在已被证明易患HSA的品种中。