Laboratoire PECSA-UMR 7195-CNRS, Université Pierre et Marie Curie, UPMC-Univ Paris 06, 4 place Jussieu, 75252 Paris cedex 05, France.
Phys Chem Chem Phys. 2014 Mar 7;16(9):4077-81. doi: 10.1039/c3cp54484b.
We report the design of new catanionic vesicles decorated with iron oxide nanoparticles, which could be used as a model system to illustrate controlled delivery of small solutes under mild hyperthermia. Efficient release of fluorescent dye rhodamine 6G was observed when samples were exposed to an oscillating magnetic field. Our system provides direct evidence for reversible permeability upon magnetic stimulation.
我们报告了新型双离子囊泡的设计,其表面修饰有氧化铁纳米粒子,可以作为模型体系来阐明在温和的热疗条件下小分子的控制释放。当样品暴露于振荡磁场中时,观察到荧光染料罗丹明 6G 的有效释放。我们的体系提供了在磁场刺激下通透性可逆变化的直接证据。