Allaoui Mohamed, Hubert Elie, Michels Jean-Jacques
Department of Biopathology, François Baclesse Cancer Center, CAEN, FRANCE.
Turk Patoloji Derg. 2014;30(1):66-8. doi: 10.5146/tjpath.2013.01205.
Malignant pilomatricoma or pilomatrical carcinoma is a rare malignant hair follicle neoplasm. This tumor is locally aggressive with increased tendency to recur, but a low metastatic potential. Its histopathological diagnosis is difficult and based on a detailed evaluation of the infiltrative nature, the importance of the mummified and necrotic cell component, atypical mitoses, and perineural or vascular invasion. Surgical wide resection is the recommended treatment. It reduces the risk of focal recurrence by 50%. Here we report two new cases including one that occurred on a lesion initially diagnosed as benign pilomatricoma.
恶性毛母质瘤或毛母质癌是一种罕见的恶性毛囊肿瘤。该肿瘤具有局部侵袭性，复发倾向增加，但转移潜能较低。其组织病理学诊断困难，基于对浸润性、木乃伊化和坏死细胞成分的重要性、非典型有丝分裂以及神经周围或血管侵犯的详细评估。推荐的治疗方法是手术广泛切除。这可将局部复发风险降低50%。在此我们报告两例新病例，其中一例发生在最初诊断为良性毛母质瘤的病变上。
