Sari Alper, Yavuzer Reha, Isik Ipek, Latifoglu Osman, Ataoglu Omur
Departments of Plastic and Reconstructive Surgery and Pathology, Gazi University, Ankara, Turkey.
Dermatol Surg. 2002 Jul;28(7):603-5.
Malherbe tumors, also known as pilomatricomas, are benign cutaneous tumors of hair matrix origin.
To discuss a rare case of multiple pilomatricoma of the head and neck region in a very young patient.
A 14-month-old baby presented with two lesions, one appearing on the preauricular region and the other on the nasolabial fold. One of the lesions showed significant ulceration.
Excisional biopsy was performed for both of the lesions. Although the histopathologic examination suggested pilomatricoma as the diagnosis, the lesion with ulcerations exhibited increased mitosis which made us consider pilomatrix carcinoma in its differential diagnosis.
Increased mitoses, an uncommon unexpected feature for pilomatricoma, can be a marker for more aggressive biologic behavior.
马尔赫贝瘤,也称为毛母质瘤,是起源于毛母质的良性皮肤肿瘤。
探讨一名非常年轻患者头颈部多发毛母质瘤的罕见病例。
一名14个月大的婴儿出现两处皮损,一处位于耳前区,另一处位于鼻唇沟。其中一处皮损有明显溃疡。
对两处皮损均进行了切除活检。尽管组织病理学检查提示诊断为毛母质瘤,但有溃疡的皮损有较多核分裂象,这使得我们在鉴别诊断中考虑毛母质癌。
核分裂象增多是毛母质瘤不常见的意外特征,可能是生物学行为更具侵袭性的标志。