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A dosimetry method for low dose rate brachytherapy by EGS5 combined with regression to reflect source strength shortage.

作者信息

Tanaka Kenichi, Tateoka Kunihiko, Asanuma Osamu, Kamo Ken-Ichi, Sato Kaori, Takeda Hiromitsu, Takagi Masaru, Hareyama Masato, Takada Jun

机构信息

Department of Medicine, Graduate School of Sapporo Medical University, South 1, West 17, Chuo-ward, Sapporo, Hokkaido 060-8556, Japan.

出版信息

J Radiat Res. 2014 May;55(3):608-12. doi: 10.1093/jrr/rrt147. Epub 2014 Jan 20.

DOI:10.1093/jrr/rrt147
PMID:24449715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4014170/
Abstract

The post-implantation dosimetry for brachytherapy using Monte Carlo calculation by EGS5 code combined with the source strength regression was investigated with respect to its validity. In this method, the source strength for the EGS5 calculation was adjusted with the regression, so that the calculation would reproduce the dose monitored with the glass rod dosimeters (GRDs) on a water phantom. The experiments were performed, simulating the case where one of two (125)I sources of Oncoseed 6711 was lacking strength by 4-48%. As a result, the calculation without regression was in agreement with the GRD measurement within 26-62%. In this case, the shortage in strength of a source was neglected. By the regression, in order to reflect the strength shortage, the agreement was improved up to 17-24%. This agreement was also comparable with accuracy of the dose calculation for single source geometry reported previously. These results suggest the validity of the dosimetry method proposed in this study.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52ec/4014170/b818abaebeda/rrt14703.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52ec/4014170/278ed34491c0/rrt14701.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52ec/4014170/8d9cfbe24172/rrt14702.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52ec/4014170/b818abaebeda/rrt14703.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52ec/4014170/278ed34491c0/rrt14701.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52ec/4014170/8d9cfbe24172/rrt14702.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52ec/4014170/b818abaebeda/rrt14703.jpg

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引用本文的文献

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J Radiat Res. 2015 Mar;56(2):366-71. doi: 10.1093/jrr/rru088. Epub 2015 Jan 24.

本文引用的文献

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J Radiat Res. 2012;53(3):439-46. doi: 10.1269/jrr.11064. Epub 2012 May 11.
2
A dosimetry study of the Oncoseed 6711 using glass rod dosimeters and EGS5 Monte Carlo code in a geometry lacking radiation equilibrium scatter conditions.在缺乏辐射平衡散射条件的几何形状中,使用玻璃棒剂量计和 EGS5 蒙特卡罗代码对 Oncoseed 6711 进行剂量学研究。
Med Phys. 2011 Jun;38(6):3069-76. doi: 10.1118/1.3590370.
3
Low-dose-rate interstitial brachytherapy preserves good quality of life in buccal mucosa cancer patients.
低剂量率间质近距离放疗可维持颊黏膜癌患者的良好生活质量。
J Radiat Res. 2011;52(5):655-9. doi: 10.1269/jrr.11025. Epub 2011 Jul 16.
4
Evaluation of the dosimetric parameters for 125I brachytherapy determined in prostate medium using CT images.使用 CT 图像评估前列腺中 125I 近距离放射治疗的剂量学参数。
J Radiat Res. 2010;51(5):553-61. doi: 10.1269/jrr.10027.
5
Experimental and Monte Carlo determination of the TG-43 dosimetric parameters for the model 9011 THINSeed brachytherapy source.实验和蒙特卡罗方法确定 9011 THINSeed 近距离放射治疗源的 TG-43 剂量学参数。
Med Phys. 2010 Apr;37(4):1681-8. doi: 10.1118/1.3360899.
6
Study of the IsoAid ADVANTAGE (125)I brachytherapy source dosimetric parameters using Monte Carlo simulation.使用蒙特卡罗模拟对IsoAid ADVANTAGE (125)I近距离放射治疗源剂量学参数的研究。
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Impact of interseed attenuation and tissue composition for permanent prostate implants.永久性前列腺植入物中种子间衰减和组织成分的影响。
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