[淋巴肉瘤患儿的干扰素缺乏综合征]
[Interferon deficiency syndrome in children with lymphosarcoma].
作者信息
Mentkevich G L, Zhdanov L V, Makhonova L A, Orlova T G
出版信息
Vopr Virusol. 1987 May-Jun;32(3):334-7.
The capacity of the peripheral blood mononuclears to produce leukocyte (alpha) and immune (gamma) interferons as well as interferon concentrations in the serum were studied in 101 children suffering from lymphosarcoma. In the blood serum of the patients interferon titres did not exceed 4 units/ml. The lowered capacity of the peripheral blood mononuclears to produce one of the interferon species in titres below 32 units/ml is a bad prognostic factor. The syndrome of interferon deficiency in children suffering from lymphosarcoma is observed in one per 5 cases.
对101例淋巴肉瘤患儿的外周血单核细胞产生白细胞（α）和免疫（γ）干扰素的能力以及血清中的干扰素浓度进行了研究。患者血清中的干扰素滴度不超过4单位/毫升。外周血单核细胞产生一种干扰素的能力降低，滴度低于32单位/毫升，这是一个不良预后因素。每5例患淋巴肉瘤的儿童中就有1例出现干扰素缺乏综合征。
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