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对于种植体植入的不同牙槽骨增量手术,是否存在特定的适应症?一项系统评价。

Are there specific indications for the different alveolar bone augmentation procedures for implant placement? A systematic review.

作者信息

Milinkovic I, Cordaro L

机构信息

Department of Periodontology and Prosthodontics, Eastman Dental Hospital, Rome, Italy.

Department of Periodontology and Prosthodontics, Eastman Dental Hospital, Rome, Italy.

出版信息

Int J Oral Maxillofac Surg. 2014 May;43(5):606-25. doi: 10.1016/j.ijom.2013.12.004. Epub 2014 Jan 19.

Abstract

Bone resorption following tooth loss often interferes with dental implant placement in a desired position, and requires additional bone augmentation procedures. Many techniques have been described to augment and reconstruct alveolar ridge width and height. The aim of this study was to systemically review whether there is evidence to provide indications for the various bone augmentation procedures based on defect dimension and type. An electronic search of the Medline database and Cochrane library, complemented by a manual search, was performed. Inclusion criteria for partial edentulism were: clinical trials on bone augmentation procedures in preparation or at the time of implant placement, reporting preoperative and postoperative dimensions of the ridge. For edentulous patients, studies were included when providing the data on ridge and defect description, or the amount of augmentation achieved. The search yielded 53 publications for partially edentulous patients and 15 publications for edentulous patients. The literature provides evidence that dehiscence and fenestrations can be treated successfully with guided bone regeneration (GBR) at the time of implant placement (mean implant survival rate (MISR) 92.2%, mean complication rate (MCR) 4.99%). In partially edentulous ridges, when a horizontal defect is present, procedures such as staged GBR (MISR 100%, MCR 11.9%), bone block grafts (MISR 98.4%, MCR 6.3%), and ridge expansion/splitting (MISR 97.4%, MCR 6.8%) have proved to be effective. Vertical defects can be treated with simultaneous and staged GBR (MISR 98.9%, MCR 13.1% and MISR 100%, MCR 6.95%, respectively), bone block grafts (MISR 96.3%, MCR 8.1%), and distraction osteogenesis (MISR 98.2%, MCR 22.4%). In edentulous patients, there is evidence that bone block grafts can be used (MISR 87.75%), and that Le Fort I osteotomies can be applied (MISR 87.9%), but associated with a high complication rate. The objective of extracting specific indications for each procedure could not be fully achieved due to the heterogeneity of the studies available. Further studies on bone augmentation procedures should report precise preoperative and postoperative measurements to enable a more exact analysis of the augmentation procedure, as well as to provide the clinician with the rationale for choosing the most indicated surgical approach.

摘要

牙齿缺失后的骨吸收常常妨碍将牙种植体植入理想位置,因此需要额外的骨增量手术。已经描述了许多用于增大和重建牙槽嵴宽度与高度的技术。本研究的目的是系统评价是否有证据能根据缺损尺寸和类型为各种骨增量手术提供适应证。我们对Medline数据库和Cochrane图书馆进行了电子检索,并辅以手工检索。部分牙列缺损的纳入标准为:关于种植体植入准备阶段或植入时骨增量手术的临床试验,报告术前和术后牙槽嵴的尺寸。对于无牙患者,当提供牙槽嵴和缺损描述数据或所实现的增量量时纳入研究。检索得到53篇关于部分牙列缺损患者的出版物和15篇关于无牙患者的出版物。文献表明,在种植体植入时,裂开和开窗可用引导骨再生(GBR)成功治疗(平均种植体存活率(MISR)92.2%,平均并发症发生率(MCR)4.99%)。在部分牙列缺损的牙槽嵴中,当存在水平缺损时,诸如分期GBR(MISR 100%,MCR 11.9%)、骨块移植(MISR 98.4%,MCR 6.3%)以及牙槽嵴扩展/劈开(MISR 97.4%,MCR 6.8%)等手术已被证明是有效的。垂直缺损可用同期和分期GBR(分别为MISR 98.9%,MCR 13.1%和MISR 100%,MCR 6.95%)、骨块移植(MISR 96.3%,MCR 8.1%)以及牵张成骨(MISR 98.2%,MCR 22.4%)治疗。在无牙患者中,有证据表明可使用骨块移植(MISR 87.75%),并且可应用Le Fort I截骨术(MISR 87.9%),但并发症发生率较高。由于现有研究的异质性,未能完全实现为每种手术提取特定适应证的目标。关于骨增量手术的进一步研究应报告精确的术前和术后测量结果,以便能更准确地分析增量手术,并为临床医生提供选择最适合手术方法的理论依据。

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