Regestein Q R
Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115.
Am J Med. 1987 Nov;83(5):909-16. doi: 10.1016/0002-9343(87)90650-4.
Sedative/hypnotic drugs for the treatment of chronic insomnia are generally considered ineffective by most experts but helpful by many patients. Occasionally, insomnia-induced debilitations may be remedied by long-term use of sedative/hypnotic drugs; some examples are given. The present discrepancy between expert and patient opinion may be derived from current research practices. The improbability that series of sedative/hypnotic drug trials will be carried out for patients with insomnia further biases against observation of rarer but clinically significant distinctions among these drugs.
