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台湾社区老年人镇静催眠药物使用情况。

Sedative-hypnotic drug use among community-dwelling elderly in Taiwan.

机构信息

Institute of Population Health Sciences,National Health Research Institutes,Zhunan,Miaoli,Taiwan.

Aesthetic-Mind Clinic,Taichung,Taiwan.

出版信息

Int Psychogeriatr. 2018 Jul;30(7):957-965. doi: 10.1017/S1041610217002940. Epub 2018 Mar 21.

Abstract

UNLABELLED

ABSTRACTBackground:Sedative-hypnotic medication use has been related to severe adverse events and risks. This study investigated the prevalence of and characteristics associated with the use of sedatives and hypnotics among community-dwelling elderly persons aged 65 years and over in Taiwan.

METHODS

A representative sample of community-dwelling adults was recruited. Clinical and sociodemographic data were collected for assessing physical, mental, and cognitive functioning and disorders. Sedatives and hypnotics use was determined via both self-reporting and prescription records. Logistic regression modeling was used to evaluate associations between sedative-hypnotic use and demographic and health status.

RESULTS

Among the 3,978 participants aged 65 years and over, the rate of sedative-hypnotic use was 19.7% (n = 785). 4.5% (n = 35) of users reported sedative-hypnotic use without a doctor's prescription. Several sociodemographic characteristics were positively associated with sedative and hypnotic use, including older age, female gender, higher education level, married status, unemployment, and current alcohol consumption. Comorbid chronic and cardiovascular diseases, mental illness, depression, pain, and sleep problems also increased the likelihood of sedative-hypnotic use.

CONCLUSIONS

This study is one of the largest pioneer studies to date to survey sedatives-hypnotics use among community-dwelling elderly. One in five community-dwelling older adults reported sedative-hypnotic drugs use in Taiwan, and about 5% of sedative and/or hypnotics usage was without a doctor's prescription. Findings could be helpful for drug-use safety interventions to identify target geriatric patients who are in general at higher risk of downstream harm associated with sedative-hypnotic use in geriatric patients.

摘要

目的

背景:镇静催眠药物的使用与严重不良事件和风险有关。本研究调查了台湾 65 岁及以上社区居住老年人镇静剂和催眠剂使用的流行率和与使用相关的特征。

方法

招募了具有代表性的社区居住成年人样本。收集了临床和社会人口统计学数据,以评估身体、精神和认知功能及障碍。通过自我报告和处方记录来确定镇静剂和催眠剂的使用情况。使用逻辑回归模型评估镇静催眠药物使用与人口统计学和健康状况之间的关联。

结果

在 3978 名 65 岁及以上的参与者中,镇静催眠药物的使用率为 19.7%(n=785)。4.5%(n=35)的使用者报告说没有医生处方就使用了镇静催眠药物。一些社会人口统计学特征与镇静和催眠药物的使用呈正相关,包括年龄较大、女性、较高的教育水平、已婚、失业和当前饮酒。合并的慢性和心血管疾病、精神疾病、抑郁、疼痛和睡眠问题也增加了使用镇静催眠药物的可能性。

结论

这是迄今为止针对台湾社区居住老年人镇静催眠药物使用情况进行调查的最大的先驱研究之一。五分之一的社区居住老年人报告说在台湾使用了镇静催眠药物,大约 5%的镇静剂和/或催眠剂的使用没有医生的处方。研究结果有助于开展药物使用安全干预措施,以确定一般处于更高风险的老年患者,这些患者与老年患者使用镇静催眠药物相关的下游危害有关。

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