Scharstein R, Johnson J F, Cook B A, Stephenson S R
Department of Radiology, Tripler Army Medical Center, Hawaii.
Am J Pediatr Hematol Oncol. 1987 Fall;9(3):219-21.
Patients with osteogenic sarcoma are at a very high risk of developing pulmonary metastatic disease. Bleomycin has recently been reported to cause pulmonary nodules mimicking metastatic disease. Our case adds what we believe to be the first report in the pediatric literature and describes new findings that we believe are so suggestive of bleomycin nodules that immediate biopsy to exclude metastatic disease may not be necessary.