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蛋氨酸和精氨酸补充对蛋白质缺乏雏鸡全身蛋白质合成的增强作用。

Enhanced whole-body protein synthesis by methionine and arginine supplementation in protein-starved chicks.

作者信息

Muramatsu T, Kato M, Tasaki I, Okumura J

机构信息

Laboratory of Animal Nutrition, School of Agriculture, Nagoya University, Japan.

出版信息

Br J Nutr. 1986 May;55(3):635-41. doi: 10.1079/bjn19860069.

DOI:10.1079/bjn19860069
PMID:2445371
Abstract
  1. The effect of supplementing with methionine alone or in combination with arginine on whole-body protein synthesis and degradation was studied in protein-starved chicks, fed on a protein-free (PF) diet, by a massive-dose injection of L-[4-3H]phenylalanine. 2. Methionine or methionine and arginine (MA) supplementation reduced body-weight loss and improved N balance compared with unsupplemented controls. 3. Whole-body protein synthesis was significantly increased both in terms of fractional rate and absolute amounts by methionine and MA addition, whereas the fractional degradation rate was unchanged. 4. No significant difference was found between methionine and MA supplementation except for energy balance of the birds. 5. It was concluded that the N-sparing effect of methionine or MA when added to a PF diet was primarily brought about by enhanced whole-body protein synthesis.
摘要
  1. 通过大剂量注射L-[4-³H]苯丙氨酸,在以无蛋白(PF)日粮喂养的蛋白质饥饿雏鸡中研究了单独补充蛋氨酸或蛋氨酸与精氨酸组合对全身蛋白质合成和降解的影响。2. 与未补充的对照组相比,补充蛋氨酸或蛋氨酸与精氨酸(MA)可减少体重减轻并改善氮平衡。3. 添加蛋氨酸和MA后,全身蛋白质合成在分数率和绝对量方面均显著增加,而分数降解率未改变。4. 除了禽类的能量平衡外,蛋氨酸和MA补充之间未发现显著差异。5. 得出的结论是,添加到PF日粮中的蛋氨酸或MA的氮节约效应主要是由全身蛋白质合成增强引起的。

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Enhanced whole-body protein synthesis by methionine and arginine supplementation in protein-starved chicks.蛋氨酸和精氨酸补充对蛋白质缺乏雏鸡全身蛋白质合成的增强作用。
Br J Nutr. 1986 May;55(3):635-41. doi: 10.1079/bjn19860069.
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Applications of chemically defined diets to the solution of nutrition problems.
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Amino Acids. 1992 Feb;2(1-2):1-12. doi: 10.1007/BF00806073.