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口腔病变的诊断一致性特征

Diagnostic concordance characteristics of oral cavity lesions.

作者信息

Tatli Ufuk, Erdoğan Özgür, Uğuz Aysun, Üstün Yakup, Sertdemır Yaşar, Damlar İbrahim

机构信息

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Çukurova University, Saricam-Balcali, 01330 Adana, Turkey.

Department of Pathology, Faculty of Medicine, Çukurova University, 01330 Adana, Turkey.

出版信息

ScientificWorldJournal. 2013 Dec 25;2013:785929. doi: 10.1155/2013/785929. eCollection 2013.

Abstract

PURPOSE

The objective of this study was to evaluate the diagnostic concordance characteristics of oral cavity lesions by comparing the clinical diagnosis of the lesions with the histopathologic diagnosis.

MATERIAL AND METHOD

A retrospective analysis was conducted on the patients, who were admitted with oral cavity pathology and underwent biopsy procedure between 2007 and 2011. The oral cavity lesions were classified into 6 different groups as odontogenic cysts, nonodontogenic cysts, odontogenic tumors, nonodontogenic tumors, malignant tumors, and precancerous lesions in accordance with the 2005 WHO classification. The diagnoses were also recategorized into 3 groups expressing prognostic implications as benign, precancerous, and malignant. The initial clinical diagnoses were compared with the histopathologic diagnoses. Data were analyzed statistically.

RESULTS

A total of 2718 cases were included. Histopathologic diagnosis did not match the clinical diagnosis in 6.7% of the cases. Nonodontogenic tumors and malignant tumors had the highest misdiagnosis rates (11.5% and 9%, resp.), followed by odontogenic tumors (7.7%), precancerous lesions (6.9%), and odontogenic cysts (4.4%). Clinicians were excelled in diagnosis of benign and precancerous lesions in clinical setting.

CONCLUSION

The detailed discordance characteristics for each specific lesion should be considered during oral pathology practice to provide early detection without delay.

摘要

目的

本研究的目的是通过比较口腔病变的临床诊断与组织病理学诊断,评估口腔病变的诊断一致性特征。

材料与方法

对2007年至2011年间因口腔病理学入院并接受活检的患者进行回顾性分析。根据2005年世界卫生组织分类,口腔病变分为牙源性囊肿、非牙源性囊肿、牙源性肿瘤、非牙源性肿瘤、恶性肿瘤和癌前病变6个不同组。诊断也重新分类为表示预后意义的3组,即良性、癌前和恶性。将初始临床诊断与组织病理学诊断进行比较。对数据进行统计学分析。

结果

共纳入2718例病例。6.7%的病例组织病理学诊断与临床诊断不匹配。非牙源性肿瘤和恶性肿瘤的误诊率最高(分别为11.5%和9%),其次是牙源性肿瘤(7.7%)、癌前病变(6.9%)和牙源性囊肿(4.4%)。临床医生在临床环境中对良性和癌前病变的诊断表现出色。

结论

在口腔病理学实践中应考虑每种特定病变的详细不一致特征,以便及时进行早期检测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c442/3886281/64632e008079/TSWJ2013-785929.001.jpg

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