卵巢癌化疗后类肉瘤病模拟癌症转移。
Sarcoidosis mimicking cancer metastasis following chemotherapy for ovarian cancer.
机构信息
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea. ; Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea.
出版信息
Cancer Res Treat. 2013 Dec;45(4):354-8. doi: 10.4143/crt.2013.45.4.354. Epub 2013 Dec 31.
We report on a rare case of sarcoidosis that developed after chemotherapy for ovarian cancer, and mimicked a cancer metastasis. A 52-year-old female diagnosed with stage III ovarian cancer underwent curative surgery and postoperative chemotherapy. Four months later, her whole-body positron emission tomography and computed tomography (CT) scan showed high uptake in the mediastinal lymph nodes, and ovarian cancer recurrence was suspected. Biopsy of the mediastinal lymph nodes and subcutaneous nodules revealed noncaseating granulomas. These lesions resolved spontaneously without treatment; however, newly developed perilymphatic and centrilobular nodules were observed on follow-up chest CT. Surgical biopsy of these lesions also showed noncaseating granulomas. She was finally diagnosed with sarcoidosis.
我们报告了一例卵巢癌化疗后发生的、类似癌症转移的罕见肉瘤样病病例。一名 52 岁女性被诊断为 III 期卵巢癌，接受了根治性手术和术后化疗。4 个月后，她的全身正电子发射断层扫描和计算机断层扫描（CT）显示纵隔淋巴结摄取增加，怀疑为卵巢癌复发。纵隔淋巴结和皮下结节活检显示非干酪样肉芽肿。这些病变未经治疗即可自行消退；然而，在随访胸部 CT 上观察到新出现的肺周和小叶中央结节。对这些病变进行的手术活检也显示出非干酪样肉芽肿。她最终被诊断为肉瘤样病。
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