Caras William E, Dillard Thomas, Baker Thomas, Pluss Jerry
Department of Medicine, Pulmonary/Critical Care Service, Madigan Army Medical Center, Tacoma, WA, USA.
South Med J. 2003 Sep;96(9):918-22. doi: 10.1097/01.SMJ.0000083858.65141.79.
In 1974, Brincker and Wilbek noted a statistically significant increase of malignant tumors among sarcoid patients and speculated that immunologic deficiencies stemming from sarcoidosis may predispose such patients to malignancy. In this article, we describe three additional cases of sarcoidosis and coexisting malignancy. The temporal presentation, radiographic features, and histologic findings are discussed in detail. The evidence for and against a proposed link between sarcoid and malignancy is reviewed.
1974年，布林克和威尔贝克指出，结节病患者中恶性肿瘤的发生率有统计学意义的增加，并推测结节病引起的免疫缺陷可能使这些患者易患恶性肿瘤。在本文中，我们描述了另外三例结节病合并恶性肿瘤的病例。详细讨论了其时间表现、影像学特征和组织学发现。对支持和反对结节病与恶性肿瘤之间存在关联的证据进行了综述。
