Coexistence of sarcoidosis and malignancy.

In 1974, Brincker and Wilbek noted a statistically significant increase of malignant tumors among sarcoid patients and speculated that immunologic deficiencies stemming from sarcoidosis may predispose such patients to malignancy. In this article, we describe three additional cases of sarcoidosis and coexisting malignancy. The temporal presentation, radiographic features, and histologic findings are discussed in detail. The evidence for and against a proposed link between sarcoid and malignancy is reviewed.