Taxol counteracts colchicine blockade of axonal transport in neurites of cultured dorsal root ganglion cells.
作者信息
Horie H, Takenaka T, Ito S, Kim S U
机构信息
Department of Physiology, Yokohama City University, School of Medicine, Japan.
出版信息
Brain Res. 1987 Sep 8;420(1):144-6. doi: 10.1016/0006-8993(87)90249-6.
PMID:2445429
Abstract
Taxol does not affect axonal transport in cultured neurites. Preincubation of this drug inhibits the effects of colchicine on axonal transport and morphology in cultured neurites. A reduction of the free tubulin density by preincubated taxol might prevent the disruption of microtubules by colchicine.
摘要
Zotero 插件