Omran Jad, Al-Dadah Ashraf, Dellsperger Kevin C
Cardiorenal Med. 2013 Oct;3(3):165-177. doi: 10.1159/000351985. Epub 2013 Jul 13.
In this review, we discuss the physiology, diagnosis and treatment of dyslipidemia in patients with chronic and end-stage renal disease. The recent important clinical trials in patients with chronic kidney disease and dyslipidemia are reviewed. Because of the lack of evidence in treating lipid abnormalities in this specific patient population, we propose that future studies should focus on the pathophysiological mechanisms and treatment of dyslipidemia in this special patient population.
在本综述中,我们讨论了慢性和终末期肾病患者血脂异常的生理学、诊断和治疗。对近期慢性肾病合并血脂异常患者的重要临床试验进行了综述。由于在这一特定患者群体中治疗血脂异常缺乏证据,我们建议未来的研究应聚焦于这一特殊患者群体血脂异常的病理生理机制和治疗。