Tasaka Akinori, Takeuchi Kai, Sasaki Hiromitsu, Yoshii Takayuki, Soeda Ryohei, Ueda Takayuki, Sakurai Kaoru
Department of Removable Prosthodontics and Gerodontology, Tokyo Dental College, Tokyo, Japan.
Department of Removable Prosthodontics and Gerodontology, Tokyo Dental College, Tokyo, Japan.
J Prosthodont Res. 2014 Jan;58(1):48-54. doi: 10.1016/j.jpor.2013.10.005. Epub 2014 Jan 20.
We investigated the influence of chewing time on salivary stress markers.
Participants performed arithmetic calculations for 30min as stress loading, followed by chewing for 0, 5, 10, or 15min. All experiments finished at 25min after stress loading. With 0-min chewing, saliva was collected before stress loading (BS), immediately after stress loading (R0), and at 5, 10, 15, and 25min after stress loading (R5, 10, 15 and 25). With 5, 10, or 15min chewing, saliva was collected at BS and R0, immediately after chewing (Ch5, 10 and 15, respectively), and 25min after stress loading (Ch5R25, Ch10R25 and Ch15R25, respectively). Salivary alpha-amylase activity and cortisol levels were measured to evaluate stress. Change in stress markers between R0 and Ch5, 10 and 15 or R25, Ch5R25, Ch10R25 and Ch15R25 were calculated.
No significant differences were observed in rate of change in alpha-amylase activity among the chewing conditions. Rate of decrease in cortisol levels was significantly greater at 15-min chewing than at 5-min chewing. Rate of decrease in cortisol levels was significantly greater at 10 and 15-min chewing than at 0-min chewing.
The present results indicate that chewing time affects the reaction of the endocrine system to mental stress, and that continuous chewing for more than 10min is effective in reducing stress.
我们研究了咀嚼时间对唾液应激标志物的影响。
参与者进行30分钟的算术计算作为应激负荷，随后咀嚼0、5、10或15分钟。所有实验在应激负荷后25分钟结束。对于0分钟咀嚼，在应激负荷前（BS）、应激负荷后立即（R0）以及应激负荷后5、10、15和25分钟（R5、10、15和25）收集唾液。对于5、10或15分钟咀嚼，在BS和R0、咀嚼后立即（分别为Ch5、10和15）以及应激负荷后25分钟（分别为Ch5R25、Ch10R25和Ch15R25）收集唾液。测量唾液α-淀粉酶活性和皮质醇水平以评估应激。计算R0与Ch5、10和15或R25、Ch5R25、Ch10R25和Ch15R25之间应激标志物的变化。
在咀嚼条件之间，α-淀粉酶活性的变化率未观察到显著差异。15分钟咀嚼时皮质醇水平的下降率显著大于5分钟咀嚼时。10和15分钟咀嚼时皮质醇水平的下降率显著大于0分钟咀嚼时。
目前的结果表明，咀嚼时间会影响内分泌系统对精神应激的反应，持续咀嚼超过10分钟对减轻应激有效。
