MOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing 100084, China.
Department of Cell Biology, University of Texas Southwestern Medical School, Dallas, TX 75390, USA.
Curr Biol. 2014 Jan 20;24(2):R75-R78. doi: 10.1016/j.cub.2013.11.043.
Cilia grow by assembling structural precursors delivered to their tips by intraflagellar transport. New work on ciliary length control indicates that, during ciliary growth, cilia send a length signal to the cytoplasm that regulates cargo loading onto the constitutively trafficking intraflagellar transport machinery.
纤毛通过组装由鞭毛内运输递送到其尖端的结构前体来生长。关于纤毛长度控制的新工作表明，在纤毛生长过程中，纤毛向细胞质发送长度信号，调节货物加载到组成型运输的鞭毛内运输机器上。
