Centro de Investigación en Sanidad Animal (CISA)-INIA, Ctra. Algete-El Casar s/n, 28130 Valdeolmos, Spain.
Division of Avian and Fish Diseases, Kimron Veterinary Institute, PO Box 12, Bet Dagan 50250, Israel.
J Gen Virol. 2014 Apr;95(Pt 4):883-887. doi: 10.1099/vir.0.061465-0. Epub 2014 Jan 23.
Bagaza virus (BAGV) and Israel turkey meningoencephalomyelitis virus (ITV) are classified in the genus Flavivirus of the family Flaviviridae. Serologically, they are closely related, belonging to the Ntaya serocomplex. Nucleotide sequences available to date consist of several complete sequences of BAGV isolates, but only partial sequences of ITV isolates. Sequence comparisons of partial envelope (E) and NS5 regions reveal a close genetic relationship between these viruses. Despite this, BAGV and ITV are considered as separate virus species in the database of the International Committee on Taxonomy of Viruses. In this work, complete nucleotide sequences for five ITV isolates are provided, thereby permitting a phylogenetic comparison with other complete sequences of flaviviruses in the Ntaya serogroup. We conclude that BAGV and ITV are the same virus species and propose that both viruses be designated by a new unified name: Avian meningoencephalomyelitis virus.
巴加病毒(BAGV)和以色列火鸡脑脊髓炎病毒(ITV)属于黄病毒科黄病毒属。血清学上,它们密切相关,属于 Ntaya 血清复合物。目前已获得的核苷酸序列包括几个 BAGV 分离株的完整序列,但只有 ITV 分离株的部分序列。部分包膜(E)和 NS5 区的序列比较显示这些病毒之间存在密切的遗传关系。尽管如此,BAGV 和 ITV 在病毒分类学国际委员会的数据库中被认为是两种不同的病毒。在这项工作中,提供了五个 ITV 分离株的完整核苷酸序列,从而可以与 Ntaya 血清群中的其他黄病毒的完整序列进行系统发育比较。我们得出结论,BAGV 和 ITV 是同一种病毒,建议用一个新的统一名称来命名这两种病毒:禽脑脊髓炎病毒。