From the Department of Trauma, Hand and Reconstructive Surgery (C.B., B.B., M.F., A.K., S.R., T.M.F.), and Orthopedics and Rheumatology (J.S.), University Hospital Giessen and Marburg, Marburg; Institute for Research in Operative Medicine (IFOM) (R.L.), University of Witten/Herdecke, Campus Cologne-Merheim, Germany.
J Trauma Acute Care Surg. 2014 Feb;76(2):366-73. doi: 10.1097/TA.0b013e3182aafd7a.
Because of a lack of evidence, the appropriate timing of surgical stabilization of thoracic and lumbar spine injuries in severely injured patients is still controversial. Data of a large international trauma register were analyzed to investigate the medical care situation of unstable spinal column fractures in patients with multiple injuries, so as to examine the outcome related to timing of surgical stabilization.
Data sets of the Trauma Registry of German Trauma Society (Deutsche Gesellschaft für Unfallchirurgie [DGU]) (1993-2010) were analyzed. The Trauma Registry of DGU is a prospective, multicenter register that provides information on severely injured patients. All patients with an Injury Severity Score (ISS) of 16 or greater caused by blunt trauma, subsequent treatment of 7 days or more, 16 years or older, and thoracic or lumbar spine injuries (spine Abbreviated Injury Scale [AIS] score ≥ 2) were included in our analysis. Patients with relevant spine injuries classified as having a spine AIS score of 3 or greater were further analyzed in terms of whether they got early (<72 hours) or late (>72 hours) surgical treatment due to unstable spinal column fractures.
Of 24,974 patients, 8,994 (36.0%) had documented spinal injuries (spine AIS score ≥ 2). A total of 1,309 patients who sustained relevant thoracic spine injuries (spine AIS score ≥ 3) and 994 patients who experienced lumbar spine trauma and classified as having spine AIS score of 3 or greater were more precisely analyzed. Of these, 68.2% and 71.0%, respectively, received an early thoracic or lumbar spine fixation. With an increase in spinal injury severity, an increase in early stabilization in the thoracic and lumbar spine was seen. In the group of patients with early surgical stabilization, significantly shorter hospital stays, shorter intensive care unit stays, fewer days on mechanical ventilation, and lower rates of sepsis were seen. In the case that additional body regions were affected, for example, when patients were critically ill, a delayed spinal stabilization was more often performed.
A spinal stabilization at an early stage (<72 hours) is presumed to be beneficial. Although some patients may require delay due to necessary medical improvement, every reasonable effort should be made to treat patients with instable spinal column fractures as soon as possible. If an early surgical treatment is feasible, severely injured patients may benefit from a shorter period of hospital treatment and a lower rate of complications.
Therapeutic study, level III.
由于缺乏证据,严重创伤患者胸腰椎损伤的手术稳定时机仍存在争议。本研究分析了一个大型国际创伤登记处的数据,以调查多发伤患者不稳定脊柱骨折的医疗情况,从而检查与手术稳定时机相关的结果。
分析德国创伤学会(Deutsche Gesellschaft für Unfallchirurgie [DGU])创伤登记处(1993-2010 年)的数据。DGU 创伤登记处是一个前瞻性、多中心登记处,提供严重创伤患者的信息。所有钝性创伤导致的损伤严重度评分(Injury Severity Score,ISS)≥16、后续治疗 7 天或以上、年龄≥16 岁和胸腰椎损伤(脊柱损伤严重度评分[Abbreviated Injury Scale,AIS]≥2)的患者均纳入本分析。进一步分析了脊柱 AIS 评分≥3 且存在不稳定脊柱骨折的相关脊柱损伤患者,这些患者根据是否因不稳定脊柱骨折接受早期(<72 小时)或晚期(>72 小时)手术治疗进行分类。
在 24974 例患者中,有 8994 例(36.0%)存在记录在案的脊柱损伤(AIS 评分≥2)。共对 1309 例存在相关胸脊柱损伤(AIS 评分≥3)和 994 例发生腰椎创伤且 AIS 评分≥3 的患者进行了更精确的分析。其中,分别有 68.2%和 71.0%的患者接受了早期胸或腰椎固定。随着脊柱损伤严重程度的增加,早期稳定胸腰椎的比例也随之增加。在接受早期手术稳定治疗的患者中,住院时间、重症监护病房停留时间、机械通气时间和脓毒症发生率均显著缩短。在合并其他部位损伤的情况下,例如患者病情严重时,更常进行延迟脊柱稳定治疗。
早期(<72 小时)进行脊柱稳定被认为是有益的。尽管一些患者可能因需要必要的医疗改善而需要延迟治疗,但应尽一切努力尽快治疗不稳定脊柱骨折患者。如果早期手术治疗可行,严重创伤患者可能受益于更短的住院治疗时间和更低的并发症发生率。
治疗研究,III 级。