Hartensuer René, Weise Alina, Breuing Jessica, Bieler Dan, Sprengel Kai, Huber-Wagner Stefan, Högel Florian
Centre of Orthopaedics, Trauma Surgery, Hand Surgery, and Sports Medicine, Centre of Acute and Emergency Medicine, Aschaffenburg-Alzenau Hospital, Aschaffenburg, Germany.
Institute for Research in Operative Medicine (IFOM), Witten/Herdecke University, Cologne, Germany.
Eur J Trauma Emerg Surg. 2025 Jan 24;51(1):70. doi: 10.1007/s00068-024-02759-6.
Our aim was to update evidence-based and consensus-based recommendations for the initial surgical management of spinal (cord) injuries in patients with multiple and/or severe injuries based on current evidence. This guideline topic is part of the 2022 update of the German Guideline on the Treatment of Patients with Multiple and/or Severe Injuries.
MEDLINE and Embase were systematically searched to May 2021. Further literature reports were obtained from clinical experts. Randomised controlled trials, prospective cohort studies, and comparative registry studies were included if they compared interventions and the timing of interventions for the initial surgical management of spinal (cord) injuries in patients with polytrauma and/or severe injuries. We considered patient-relevant clinical outcomes such as mortality, complication rates, and lengths of stay. Risk of bias was assessed using NICE 2012 checklists. The evidence was synthesised narratively, and expert consensus was used to develop recommendations and determine their strength.
Seven new studies were identified. All studies compared different moments for the initial surgical management of spinal injuries. Three recommendations were modified, and three additional recommendations were developed. All achieved strong consensus.
The following key recommendations are made. (1) Patients with spinal injuries or deformities with confirmed or assumed neurological deficits which can be treated operatively should undergo surgery as soon as possible (ideally on day 1) if their other medical conditions permit. (2) If suggested by fracture morphology with spinal canal compression or translational injury and if spinal neurological damage cannot be ruled out, assume the presence of spinal neurological damage until it can be ruled out. (3) In the absence of neurological signs and/or symptoms, unstable spinal injuries should be treated by early surgical stabilization based on the patient's overall condition. (4) Depending on the injury, an anterior and/or posterior approach or, in exceptional cases, a halo fixation device can be used to stabilize the cervical spine. (5) Posterior internal fixation should be used as the primary surgical technique for stabilizing injuries to the thoracic and lumbar spine.
我们的目标是基于当前证据,更新针对多发伤和/或重伤患者脊柱(脊髓)损伤初始手术治疗的循证和基于共识的建议。本指南主题是《德国多发伤和/或重伤患者治疗指南》2022年更新的一部分。
系统检索MEDLINE和Embase至2021年5月。从临床专家处获取更多文献报告。纳入随机对照试验、前瞻性队列研究和比较登记研究,条件是它们比较了多发伤和/或重伤患者脊柱(脊髓)损伤初始手术治疗的干预措施及干预时机。我们考虑了与患者相关的临床结局,如死亡率、并发症发生率和住院时间。使用英国国家卫生与临床优化研究所(NICE)2012年清单评估偏倚风险。对证据进行叙述性综合,并利用专家共识制定建议并确定其强度。
确定了七项新研究。所有研究均比较了脊柱损伤初始手术治疗的不同时机。修改了三项建议,并制定了另外三项建议。所有建议均达成了强烈共识。
提出以下关键建议。(1)对于已确诊或疑似存在可手术治疗的神经功能缺损的脊柱损伤或畸形患者,若其其他病情允许,应尽快(理想情况下在第1天)接受手术。(2)如果骨折形态提示存在椎管受压或平移损伤,且不能排除脊髓神经损伤,则在排除之前应假定存在脊髓神经损伤。(3)在没有神经体征和/或症状的情况下,对于不稳定的脊柱损伤,应根据患者的整体状况尽早进行手术固定。(4)根据损伤情况,可采用前路和/或后路手术,或在特殊情况下使用头环固定装置来稳定颈椎。(5)后路内固定应作为稳定胸腰椎损伤的主要手术技术。