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颅面区域骨瘤:病例系列及文献综述

Osteomas of the craniofacial region: A case series and review of literature.

作者信息

Gundewar Sagar, Kothari Deepak S, Mokal Nitin J, Ghalme Amol

机构信息

Department of Plastic Surgery, G.T Hospital, Mumbai, India.

Department of Plastic Surgery, J. J. Hospital, Mumbai, India.

出版信息

Indian J Plast Surg. 2013 Sep;46(3):479-85. doi: 10.4103/0970-0358.121982.

DOI:10.4103/0970-0358.121982
PMID:24459335
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3897090/
Abstract

OBJECTIVE

To discuss the clinical presentation, diagnosis and management of osteomas involving the craniomaxillofacial region.

MATERIALS AND METHODS

This study was conducted from June 2004 to March 2012 at our institute. A total of 12 cases between the ages of 10 and 50 years were managed with surgical excision and reconstruction. The criteria used to diagnose osteoma included radiographic and clinical features and histological confirmation of the specimen. The total follow-up period ranged from 6 to 24 months.

RESULTS

Out of 12 osteomas, 10 were peripheral and 2 were centrally located. Mandible involvement was seen in six patients, four involved the orbit, one the frontal bone and one the frontal bone with the skull base. All patients undergoing excision and reconstruction had a favourable aesthetic and functional outcome. There were no recurrences and no post-operative complications.

CONCLUSION

Osteomas affect all age groups with no sex predilection and are usually clinically asymptomatic till they become large in size. Surgical excision and appropriate reconstruction is the mainstay of management. Surgery is indicated when lesion is symptomatic or actively growing and the surgical approach for exposure of the lesion should be case specific.

摘要

目的

探讨累及颅颌面区域骨瘤的临床表现、诊断及治疗方法。

材料与方法

本研究于2004年6月至2012年3月在我院开展。对12例年龄在10至50岁之间的患者进行了手术切除及重建治疗。诊断骨瘤的标准包括影像学和临床特征以及标本的组织学确认。总随访期为6至24个月。

结果

12例骨瘤中,10例为外周型,2例为中心型。6例患者下颌骨受累,4例累及眼眶,1例累及额骨,1例累及额骨及颅底。所有接受切除及重建的患者在美学和功能方面均取得良好效果。无复发及术后并发症。

结论

骨瘤可发生于所有年龄组,无性别倾向,通常在瘤体增大之前临床上无症状。手术切除及适当重建是主要治疗方法。当病变有症状或处于活跃生长状态时需进行手术,且暴露病变的手术入路应根据具体病例而定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8af1/3897090/06181a254b87/IJPS-46-479-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8af1/3897090/386b2f0fe42f/IJPS-46-479-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8af1/3897090/53f58cad1cfd/IJPS-46-479-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8af1/3897090/cae7f84477ac/IJPS-46-479-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8af1/3897090/06181a254b87/IJPS-46-479-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8af1/3897090/386b2f0fe42f/IJPS-46-479-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8af1/3897090/53f58cad1cfd/IJPS-46-479-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8af1/3897090/cae7f84477ac/IJPS-46-479-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8af1/3897090/06181a254b87/IJPS-46-479-g005.jpg

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J Oral Pathol Med. 2008 Jan;37(1):38-42. doi: 10.1111/j.1600-0714.2007.00590.x.
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Peripheral osteoma of the maxillofacial region. Diagnosis and management: a study of 14 cases.颌面部周围骨瘤。诊断与治疗:14例研究
J Clin Med. 2021 Nov 27;10(23):5584. doi: 10.3390/jcm10235584.
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Novel Mutation in Gene Associated with Multiple Osteomas in a Family and Review of Genotype-Phenotype Correlations of Extracolonic Manifestations in Gardner Syndrome.一个家族中与多发性骨瘤相关基因的新突变及加德纳综合征结肠外表现的基因型-表型相关性综述
Diagnostics (Basel). 2021 Aug 28;11(9):1560. doi: 10.3390/diagnostics11091560.
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Giant craniofacial osteoma with orbital invasion.巨大颅面骨瘤伴眼眶侵犯。
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