Department of Economics and Finance, College of Business Administration, Kwandong University, Gangneung, Korea.
Department of Urology, National Police Hospital, Seoul, Korea.
World J Mens Health. 2013 Dec;31(3):232-8. doi: 10.5534/wjmh.2013.31.3.232. Epub 2013 Dec 24.
Type of work might be related to insulin resistance and the metabolic syndrome (MetS). However, scant data are available. We performed this study to investigate whether the prevalence of MetS and insulin resistance differed according to occupation in middle-aged men.
In all, 2,348 men in their 40s~50s who had participated in the Korean National Health and Nutrition Examination Survey IV were included and were classified into two groups according to the type of work (manual worker vs. non-manual worker). Diagnosis of MetS required satisfying three or more of the National Cholesterol Education Program-Adult Treatment Panel III criteria. Fasting insulin, the glucose/insulin ratio (G/I ratio), and the homeostasis model assessment of insulin resistance (HOMA-IR) were used to estimate the insulin resistance. We used the Mann-Whitney test, χ(2) tests, multiple linear regression test, and logistic regression analyses to examine the relationships.
Age was significantly higher in the manual worker group. Body mass index was significantly lower in the manual worker group. Rates of current smoking and frequent drinking were higher in the manual worker group. In terms of surrogate markers of insulin resistance, the age-adjusted mean of fasting insulin, G/I ratio, and HOMA-IR indicated that lower insulin resistance was significantly related to manual work. After adjusting for age and other confounding factors, non-manual workers had a higher risk of the MetS than manual workers. The odds ratio in relation to MetS was significantly lower in the manual workers.
MetS and impaired insulin resistance are significantly related to non-manual work in middle-aged Korean men.
工作类型可能与胰岛素抵抗和代谢综合征（MetS）有关。然而，可用的数据很少。我们进行这项研究是为了调查中年男性的职业是否与 MetS 和胰岛素抵抗的患病率有关。
共纳入 2348 名 40 多岁至 50 多岁的韩国国民健康与营养调查 IV 参与者，并根据工作类型（体力劳动者与非体力劳动者）将其分为两组。MetS 的诊断需要满足三个或更多的国家胆固醇教育计划-成人治疗小组 III 标准。空腹胰岛素、葡萄糖/胰岛素比（G/I 比）和稳态模型评估的胰岛素抵抗（HOMA-IR）用于估计胰岛素抵抗。我们使用曼-惠特尼检验、χ²检验、多元线性回归检验和逻辑回归分析来检验关系。
体力劳动者组的年龄明显较高。体力劳动者组的体重指数明显较低。体力劳动者组的当前吸烟率和频繁饮酒率较高。在胰岛素抵抗的替代标志物方面，空腹胰岛素、G/I 比和 HOMA-IR 的年龄调整均值表明，较低的胰岛素抵抗与体力劳动显著相关。在调整年龄和其他混杂因素后，非体力劳动者患 MetS 的风险高于体力劳动者。与 MetS 相关的比值比在体力劳动者中明显较低。
在中年韩国男性中，MetS 和胰岛素抵抗受损与非体力劳动显著相关。
