Ozsahin Mustafa, Buyukkaya Ramazan, Besir Fahri Halit, Onder Halil Ibrahim, Erdogmus Besir, Ataoglu Safinaz, Güclü Derya, Kolukisa Rumeysa
a Department of Physical Medicine and Rehabilitation , Medical School of Duzce University , Duzce , Turkey .
b Department of Radiology , Medical School of Duzce University , Duzce , Turkey , and.
Semin Ophthalmol. 2015;30(5-6):360-3. doi: 10.3109/08820538.2013.874489. Epub 2014 Jan 24.
To analyze the hemodynamic features of orbital blood flow velocities using Doppler ultrasonography in ankylosing spondiylitis (AS) patients, as well as to compare these results with those of healthy controls.
33 AS patients and 32 healthy controls were consecutively included in the study groups. The same radiologist performed ocular blood flow measurements. Peak systolic velocity (PSV), end diastolic velocity (EDV), and resistive index (RI) were measured in the central retinal artery (CRA), posterior ciliary arteries (PCAs), and ophthalmic artery (OA). Resistive index was used to assess arterial resistance; it was automatically calculated as RI [(PSV-EDV)/PSV].
There were no significant differences in the PSV, EDV, and RI of the OA, CRA, and PCAs between AS patients and controls.
This result suggests no possible contributory role of vascular structures in formation of uveitis in AS. We believe that our preliminary results need to be complemented with further studies, particularly including AS patients with uveitis and rheumatic diseases with other ocular involvement.
利用多普勒超声分析强直性脊柱炎(AS)患者眼眶血流速度的血流动力学特征,并将这些结果与健康对照者的结果进行比较。
33例AS患者和32例健康对照者连续纳入研究组。由同一位放射科医生进行眼部血流测量。在视网膜中央动脉(CRA)、睫状后动脉(PCA)和眼动脉(OA)中测量收缩期峰值速度(PSV)、舒张末期速度(EDV)和阻力指数(RI)。阻力指数用于评估动脉阻力;它自动计算为RI[(PSV - EDV)/PSV]。
AS患者与对照组之间,OA、CRA和PCA的PSV、EDV和RI无显著差异。
该结果表明血管结构在AS性葡萄膜炎形成中可能不起作用。我们认为我们的初步结果需要进一步研究来补充,特别是纳入患有葡萄膜炎的AS患者以及伴有其他眼部受累的风湿性疾病患者。