以高钙血症和血清甲状腺激素水平假性正常化表现的“淡漠型”甲状腺毒症
'Apathetic' thyrotoxicosis presenting with hypercalcaemia and spurious normalization of serum thyroid hormone levels.
作者信息
Ralston S H, Fraser W D, Soukop M, McKillop J H
机构信息
University Department of Medicine, Glasgow Royal Infirmary, UK.
出版信息
Postgrad Med J. 1987 Apr;63(738):269-71. doi: 10.1136/pgmj.63.738.269.
A patient with thyrotoxicosis presented with weight loss and hypercalcaemia, leading to an erroneous diagnosis of occult malignant disease. Intercurrent illness and drug treatment of hypercalcaemia in this patient caused a depression of circulating thyroid hormone levels, leading to a delay in diagnosis. Radionuclide studies of thyroid function, in contrast, consistently suggested a thyrotoxic state. It is suggested that in this situation, radionuclide studies may give a more accurate assessment of thyroid status than biochemical tests, which may be difficult to interpret in the presence of non-thyroidal illness.
一名甲状腺毒症患者出现体重减轻和高钙血症，导致误诊为隐匿性恶性疾病。该患者的并发疾病和高钙血症的药物治疗导致循环甲状腺激素水平降低，从而延误了诊断。相比之下，甲状腺功能的放射性核素研究一直提示甲状腺毒症状态。建议在这种情况下，放射性核素研究可能比生化检查能更准确地评估甲状腺状态，因为在存在非甲状腺疾病时，生化检查可能难以解释。
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