Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, Chapel Hill, North Carolina; Birmingham/Atlanta Geriatric Research, Education, and Clinical Center, Birmingham Department of Veterans Affairs Medical Center, and the Division of Gerontology, Geriatrics, and Palliative Care, Department of Medicine, the School of Public Health, and the Division of Urogynecology and Pelvic Reconstructive Surgery, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama; and the Division of General Medicine and Geriatrics, Department of Medicine, Emory University, Atlanta, Georgia.
Obstet Gynecol. 2014 Jan;123(1):141-148. doi: 10.1097/AOG.0000000000000057.
To estimate the prevalence and trends of these pelvic floor disorders in U.S. women from 2005 to 2010.
We used the National Health and Nutritional Examination Survey from 2005-2006, 2007-2008, and 2009-2010. A total of 7,924 nonpregnant women (aged 20 years or older) were categorized as having: urinary incontinence (UI)-moderate to severe (3 or higher on a validated UI severity index, range 0-12); fecal incontinence-at least monthly (solid, liquid, or mucus stool); and pelvic organ prolapse-seeing or feeling a bulge. Potential risk factors included age, race and ethnicity, parity, education, poverty income ratio, body mass index ([BMI] less than 25, 25-29, 30 or greater), comorbidity count, and reproductive factors. Using appropriate sampling weights, weighted χ analysis and multivariable logistic regression models with odds ratios and 95% confidence intervals (95% CIs) were reported.
The weighted prevalence rate of one or more pelvic floor disorders was 25.0% (95% CI 23.6-26.3), including 17.1% (95% CI 15.8-18.4) of women with moderate-to-severe UI, 9.4% (95% CI 8.6-10.2) with fecal incontinence, and 2.9% (95% CI 2.5-3.4) with prolapse. From 2005 to 2010, no significant differences were found in the prevalence rates of any individual disorder or for all disorders combined (P>.05). After adjusting for potential confounders, higher BMI, greater parity, and hysterectomy were associated with higher odds of one or more pelvic floor disorders.
Although rates of pelvic floor disorders did not change from 2005 to 2010, these conditions remain common, with one fourth of adult U.S. women reporting at least one disorder.
III.
评估 2005 年至 2010 年美国女性中这些盆底疾病的流行率和趋势。
我们使用了 2005-2006 年、2007-2008 年和 2009-2010 年的全国健康和营养调查数据。共有 7924 名未怀孕的妇女(年龄在 20 岁或以上)被分为以下几类:尿失禁(UI)-中度至重度(在经过验证的 UI 严重程度指数上得分为 3 或更高,范围 0-12);粪便失禁-至少每月(固体、液体或粘液粪便);和盆腔器官脱垂-看到或感觉到肿块。潜在的危险因素包括年龄、种族和民族、产次、教育程度、贫困收入比、体重指数(BMI)[BMI 小于 25、25-29、30 或更高]、合并症数量和生殖因素。使用适当的抽样权重,报告了加权 χ 分析和多变量逻辑回归模型的比值比和 95%置信区间(95%CI)。
一种或多种盆底疾病的加权患病率为 25.0%(95%CI 23.6-26.3),包括 17.1%(95%CI 15.8-18.4)的中度至重度 UI 女性、9.4%(95%CI 8.6-10.2)的粪便失禁女性和 2.9%(95%CI 2.5-3.4)的脱垂女性。从 2005 年到 2010 年,任何一种单一疾病或所有疾病的患病率均无显著差异(P>.05)。在调整了潜在的混杂因素后,较高的 BMI、较高的产次和子宫切除术与更高的一种或多种盆底疾病的几率相关。
尽管 2005 年至 2010 年盆底疾病的发病率没有变化,但这些疾病仍然很常见,四分之一的美国成年女性报告至少有一种疾病。
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