Gajbhiye Ashok Surybhanji, Meshram M M, Kathod Amrish P
Department of General Surgery, Indira Gandhi Government Medical College, Central Avenue road, Nagpur, -18 Maharashtra India ; Plot no- 54, kalpataru nagar, Besa Road, Nagpur, -34 Manewada India.
Department of General Surgery, Indira Gandhi Government Medical College, Central Avenue road, Nagpur, -18 Maharashtra India.
Indian J Surg. 2013 Dec;75(6):444-8. doi: 10.1007/s12262-012-0532-6. Epub 2012 Jul 12.
Evaluation of platelet count and its significance in early detection of post burn septicemia for commencement of timely vigorous treatment against it. Studies investigating the role of platelets and platelet count in burn patients are rare, rather old and mostly presenting case reports. Septicemia is the most important cause of mortality in burns. Burn patients can only be saved if septicemia is detected early which requires very sensitive prognostic indicator. Total 594 adult burn patients were studied, by observing them for septicemia and studying their subsequent platelet counts using visual method. In non-survivors (256) gradual decline in platelet count was observed and minimal platelet count was observed before death of the patient, while in survivors (338) gradual rise in platelet count was observed. No significant variation observed in other laboratory parameters such as total neutrophil count and serum creatinine. In significant number of non survivor (62.11%) platelet count was low before their death and in significant number of survivor (86.09%) platelet count was normal before their discharge. Thus it is conclude that serial declining platelet count is a very sensitive prognostic factor in early detection of post burn septicemia.
评估血小板计数及其在烧伤后败血症早期检测中的意义,以便及时开展积极治疗。关于血小板及血小板计数在烧伤患者中作用的研究很少,且年代久远,大多为病例报告。败血症是烧伤患者死亡的最重要原因。只有早期检测到败血症才能挽救烧伤患者,这需要非常敏感的预后指标。共对594例成年烧伤患者进行了研究,通过观察他们是否发生败血症,并采用视觉方法研究其随后的血小板计数。在非幸存者(256例)中,观察到血小板计数逐渐下降,且在患者死亡前观察到最低血小板计数,而在幸存者(338例)中,观察到血小板计数逐渐上升。在其他实验室参数如总中性粒细胞计数和血清肌酐方面未观察到显著变化。在大量非幸存者(62.11%)死亡前血小板计数较低,而在大量幸存者(86.09%)出院前血小板计数正常。因此得出结论,连续下降的血小板计数是烧伤后败血症早期检测中非常敏感的预后因素。