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[与爱泼斯坦-巴尔病毒相关的噬血细胞综合征。复苏病房的一例病例介绍及治疗]

[Hemophagocytic syndrome associated with Epstein-Barr virus. Presentation of a case and treatment in the Resuscitation Unit].

作者信息

Figueiredo González O, Iglesias Fernández M, Río Gómez A, Ulibarrena Redondo C, Casas García M L

机构信息

Servicio de Anestesiología y Reanimación, Complexo Hospitalario de Ourense, Ourense, España.

Servicio de Hematología y Hemoterapia, Complexo Hospitalario de Ourense, Ourense, España.

出版信息

Rev Esp Anestesiol Reanim. 2014 Dec;61(10):571-4. doi: 10.1016/j.redar.2013.11.017. Epub 2014 Jan 24.

Abstract

We report the case of a 17 year old male patient, who was admitted to the Resuscitation Unit with the diagnosis of hemophagocytic syndrome, associated with infection by Epstein-Barr virus with unfavorable outcome. Hemophagocytic syndrome is a pathological immune activation syndrome due to the production/uncontrolled modulation of some cytokines. Its clinical signs and symptoms, defined by consensus criteria HLH-2004, are not pathognomonic, and often appear sequentially, thus suspicion should be followed by aggressive supportive therapy combined with early specific treatment of the triggering factor, as it is the only way to improve survival in patients with multiple organic failure as a result.

摘要

我们报告了一例17岁男性患者的病例,该患者因噬血细胞综合征诊断入住复苏病房,与EB病毒感染相关,预后不佳。噬血细胞综合征是一种由于某些细胞因子产生/不受控制的调节导致的病理性免疫激活综合征。其临床体征和症状,根据HLH - 2004共识标准定义,并非特异性的,且常相继出现,因此一旦怀疑,应采取积极的支持治疗并结合对触发因素的早期特异性治疗,因为这是改善多器官功能衰竭患者生存的唯一途径。

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