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轻度创伤性脑损伤老年患者的死亡率较高:一项全国性队列研究。

Higher mortality rates among the elderly with mild traumatic brain injury: a nationwide cohort study.

作者信息

Cheng Po-Liang, Lin Hsin-Yi, Lee Yi-Kung, Hsu Chen-Yang, Lee Ching-Chih, Su Yung-Cheng

机构信息

Emergency Department, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No,2, Minsheng Rd, Dalin Township, Chiayi County 622, Taiwan.

出版信息

Scand J Trauma Resusc Emerg Med. 2014 Jan 28;22:7. doi: 10.1186/1757-7241-22-7.

Abstract

BACKGROUND

It is known that the risk of death in elderly patients with moderate to severe traumatic brain injury is increased. However, the relationship between mild traumatic brain injury and death has never been established. We investigated the mortality rates of older patients with mild traumatic brain injury in Taiwan to evaluate if there is a higher risk of death compared with the general population.

METHODS

We utilized a sampled National Health Insurance claims database containing one million beneficiaries. We followed all adult beneficiaries older than 65 years from January 1, 2005 till December 31, 2009 to see if they died. We further identified patients with mild traumatic brain injury and compared their risk of death with the general population.

RESULTS

We identified 5997 patients with mild traumatic brain injury and 84,117 patients without mild traumatic brain injury. After controlling for age, gender, urbanization level, socioeconomic status, diabetes, hypertension, history of alcohol intoxication, history of ischemic stroke, history of intracranial hemorrhage, malignancies, dementia and Charlson Comorbidity Index score, the adjusted hazard ratio was 1.25 (95% confidence interval, 1.16-1.34).

CONCLUSIONS

Mild traumatic brain injury is an independent significant risk factor for death in the elderly.

摘要

背景

已知中度至重度创伤性脑损伤的老年患者死亡风险会增加。然而,轻度创伤性脑损伤与死亡之间的关系尚未确立。我们调查了台湾轻度创伤性脑损伤老年患者的死亡率,以评估与普通人群相比是否存在更高的死亡风险。

方法

我们使用了一个包含100万受益人的抽样国民健康保险理赔数据库。我们追踪了2005年1月1日至2009年12月31日所有65岁以上的成年受益人,看他们是否死亡。我们进一步确定了轻度创伤性脑损伤患者,并将他们的死亡风险与普通人群进行比较。

结果

我们确定了5997例轻度创伤性脑损伤患者和84117例无轻度创伤性脑损伤患者。在控制了年龄、性别、城市化水平、社会经济地位、糖尿病、高血压、酒精中毒史、缺血性中风史、颅内出血史、恶性肿瘤、痴呆和查尔森合并症指数评分后,调整后的风险比为1.25(95%置信区间,1.16 - 1.34)。

结论

轻度创伤性脑损伤是老年人死亡的一个独立显著风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3960/3906770/58f43162ae71/1757-7241-22-7-1.jpg

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