Centre Antoine Lacassagne, Breast Cancer and Reconstructive Surgery Unit, France.
Centre Antoine Lacassagne, Breast Cancer and Reconstructive Surgery Unit, France.
Eur J Surg Oncol. 2014 Apr;40(4):449-53. doi: 10.1016/j.ejso.2014.01.002. Epub 2014 Jan 18.
A prospective study was lead in order to analyze the accuracy of an X-ray device settled in the operating room for margin assessment, when performing breast-conserving surgery.
One hundred and seventy patients were included. All lesions were visible on the preoperative mammograms. An intraoperative X-ray of the lumpectomy specimen was systematically performed for margins assessment. Final histological data were collected and the accuracy of intraoperative specimen radiography (IOSR) for margin assessment was analyzed.
IOSR allowed an evaluation of margins status in 155 cases (91.2%). After final histological examination, the positive margins rate would have been 6.5% if margin assessment had relied only on IOSR.
Margin assessment with a two-dimensional X-ray device would have allowed the achievement of negative margins in 93.5% of the cases. Moreover, this procedure allows important time-saving and could have a substantial economical impact.
为了分析在手术室中使用 X 射线设备评估保乳手术切缘的准确性，进行了一项前瞻性研究。
共纳入 170 例患者。所有病变均在术前乳房 X 光片上可见。对乳房肿瘤切除术标本进行了系统的术中 X 射线检查，以评估切缘。收集最终的组织学数据，并分析术中标本放射学（IOSR）评估切缘的准确性。
IOSR 能够评估 155 例（91.2%）的切缘状态。在最终的组织学检查后，如果仅依靠 IOSR 评估切缘，阳性切缘率将为 6.5%。
使用二维 X 射线设备评估切缘可以使 93.5%的病例达到阴性切缘。此外，该程序可以节省大量时间，并且具有重要的经济影响。
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