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跨性别与生殖。

Transgenderism and reproduction.

作者信息

TʼSjoen Guy, Van Caenegem Eva, Wierckx Katrien

机构信息

aDepartment of Endocrinology bCenter for Sexology and Gender problems, Ghent University Hospital, Ghent, Belgium.

出版信息

Curr Opin Endocrinol Diabetes Obes. 2013 Dec;20(6):575-9. doi: 10.1097/01.med.0000436184.42554.b7.

Abstract

PURPOSE OF REVIEW

The development of new reproductive medicine techniques creates opportunities for preserving fertility in transgender persons. Before, losing fertility was accepted as the price to pay for transitioning.

RECENT FINDINGS

The desire for children is present in many trans persons, as in the general population. Ethical concerns are sometimes raised against the preservation of fertility; however, the only unique aspect of this group is the gender transition of one of the parents. All other elements such as same sex parenthood, use of donor gametes, social stigma, etc., can be found in other groups of parents. Not all reproductive options for all trans persons are equal because not only the gametes are of importance, but also the sex of the (future) partner. In trans women, the best option to preserve gametes is cryopreservation of sperm by preference initiated before starting hormonal therapy. In trans men, donor sperm is most often used, but in theory, there are three options available to preserve fertility: oocyte banking, embryo banking and banking of ovarian tissue.

SUMMARY

Fertility is possible for both trans men and women, but it requires timely cryopreservation of gametes or stopping cross-sex hormones and possible fertility treatments which are costly and may be unpleasant. Centers should elucidate their policy and inform trans persons on the possibilities and limitations.

摘要

综述目的

新的生殖医学技术的发展为跨性别者保留生育能力创造了机会。以前,失去生育能力被认为是变性所要付出的代价。

最新发现

与普通人群一样,许多跨性别者都有生育子女的愿望。有时会有人对保留生育能力提出伦理方面的担忧;然而,这个群体唯一独特的方面是父母一方的性别转变。其他所有因素,如同性父母身份、使用捐赠配子、社会污名等,在其他父母群体中也能找到。并非所有跨性别者的生殖选择都是平等的,因为不仅配子很重要,(未来)伴侣的性别也很重要。对于跨性别女性,保留配子的最佳选择是优先在开始激素治疗前冷冻精子。对于跨性别男性,最常使用捐赠精子,但理论上有三种保留生育能力的选择:卵子库保存、胚胎库保存和卵巢组织库保存。

总结

跨性别男性和女性都有可能生育,但这需要及时冷冻配子,或者停止使用跨性别激素以及可能进行的成本高昂且可能令人不适的生育治疗。各中心应阐明其政策,并告知跨性别者相关的可能性和局限性。

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