Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.
Children's National Medical Center, Washington, DC.
J Clin Endocrinol Metab. 2020 Oct 1;105(10):3335-45. doi: 10.1210/clinem/dgaa529.
Comprehensive care for transgender and gender nonbinary patients has been a priority established by the World Professional Association for Transgender Health. Because pubertal suppression, gender-affirming hormone therapy, and antiandrogen therapy used alone or in combination during medical transition can affect gonadal function, understanding the effects these treatments have on fertility potential is important for practitioners caring for transgender and gender nonbinary patients. In this review, we outline the impacts of gender-affirming treatments on fertility potential and discuss the counseling and the treatment approach for fertility preservation and/or family building in transgender and gender nonbinary individuals.
跨性别和性别非二元患者的综合护理一直是世界跨性别健康专业协会确定的优先事项。由于青春期抑制、性别肯定激素治疗和雄激素拮抗剂治疗在医学转变期间单独或联合使用会影响性腺功能,因此了解这些治疗方法对生育潜力的影响对于照顾跨性别和性别非二元患者的从业者很重要。在这篇综述中,我们概述了性别肯定治疗对生育潜力的影响,并讨论了跨性别和性别非二元个体的生育保存和/或家庭建设的咨询和治疗方法。