Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, New York University Langone Health, 111 Broadway, 2nd Floor, New York, NY 10006, USA.
Division of Reproductive Endocrinology and Infertility, Department of Obstetrics & Gynecology, New York University Langone Prelude Fertility Center, 159 East 53rd Street, 3rd Floor, New York, NY 10022, USA.
Endocrinol Metab Clin North Am. 2024 Sep;53(3):471-482. doi: 10.1016/j.ecl.2024.05.008.
Many transgender and gender diverse (TGD) individuals will be considering gender-affirming treatments during their reproductive lifespan. These medically necessary treatments have a negative impact on reproductive potential. All TGD individuals should be counseled regarding fertility. Options for fertility preservation for individuals who have undergone puberty include mature oocyte, embryo, and sperm cryopreservation. In prepubertal individuals, ovarian tissue cryopreservation may be considered, but testicular tissue cryopreservation remains experimental only. While there have been advances in the technology and standardization of reproductive health care for this population, many gaps remain in our knowledge which require further research.
许多跨性别和性别多样化（TGD）个体在生育期会考虑进行性别肯定治疗。这些医学上必需的治疗会对生育潜能产生负面影响。所有 TGD 个体都应接受生育能力咨询。对于已经经历青春期的个体，可选择成熟卵母细胞、胚胎和精子冷冻保存。对于青春期前的个体，可考虑卵巢组织冷冻保存，但睾丸组织冷冻保存仍仅处于实验阶段。尽管在为这一人群提供生殖保健方面的技术和标准化方面取得了进展，但我们的知识仍存在许多空白，需要进一步研究。
