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[促红细胞生成素对大鼠网织红细胞计数及成熟度分布的影响]

[Modification of reticulocyte count and distribution of degree of maturity by erythropoietin in the rat].

作者信息

Eder H, Wiemer U

机构信息

Institut für Veterinär-Physiologie der Justus-Liebig-Universität Giessen, BRD.

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1987;114(4):517-22.

PMID:2446992
Abstract

By means of an automatic system for reticulocyte analysis (Auras) the effect of administering 50 IU of intraperitoneal erythropoietin on the number of reticulocytes and the distribution of the maturation degree of reticulocytes was investigated on Wistar rats for 28 days. A single administration of erythropoietin will lead to a rapid increase in the absolute number of reticulocytes and to changes in the distribution of the maturation degree within the first five days. The maximum of the reticulocyte number can be observed on the third to fourth day after application. Even on the second day after administering erythropoietin the measuring numbers of the distribution of maturation degree indicate maximal changes, the distribution quotient being particularly evident.

摘要

通过一个网织红细胞自动分析系统(Auras),研究了给Wistar大鼠腹腔注射50国际单位促红细胞生成素28天对网织红细胞数量及网织红细胞成熟度分布的影响。单次注射促红细胞生成素会导致网织红细胞绝对数量迅速增加,并在头五天内使成熟度分布发生变化。在注射后第三天至第四天可观察到网织红细胞数量达到最大值。即使在注射促红细胞生成素后的第二天,成熟度分布的测量数值也显示出最大变化,分布商尤为明显。

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Folia Haematol Int Mag Klin Morphol Blutforsch. 1987;114(4):517-22.
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引用本文的文献

1
[Automated microfluorometric absolute count and maturation analysis of reticulocytes].
Klin Wochenschr. 1989 Oct 17;67(20):1048-57. doi: 10.1007/BF01727007.
2
A dose-dependent effect of recombinant erythropoietin on the reticulocyte population of rats.重组促红细胞生成素对大鼠网织红细胞群体的剂量依赖性效应。
Blut. 1989 Aug;59(2):184-7. doi: 10.1007/BF00320065.